Intra-articular sprifermin reduces cartilage loss in addition to increasing cartilage gain independent of location in the femorotibial joint: post-hoc analysis of a randomised, placebo-controlled phase II clinical trial.

Autor: Eckstein F; Department of Imaging and Functional Musculoskeletal Research, Institute of Anatomy & Cell Biology, Paracelsus Medical University, Salzburg, Austria felix.eckstein@pmu.ac.at.; Chondrometrics GmbH, Ainring, Germany.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Paracelsus Medical University, Salzburg, Austria., Kraines JL; Global Clinical Development - Immunology, EMD Serono Research and Development Institute, Inc, Billerica, Massachusetts, USA., Aydemir A; Global Biostatistics and Epidemiology, EMD Serono Reserach and Development Institute, Inc, Billerica, Massachusetts, USA., Wirth W; Department of Imaging and Functional Musculoskeletal Research, Institute of Anatomy & Cell Biology, Paracelsus Medical University, Salzburg, Austria.; Chondrometrics GmbH, Ainring, Germany.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Paracelsus Medical University, Salzburg, Austria., Maschek S; Department of Imaging and Functional Musculoskeletal Research, Institute of Anatomy & Cell Biology, Paracelsus Medical University, Salzburg, Austria.; Chondrometrics GmbH, Ainring, Germany., Hochberg MC; University of Maryland School of Medicine, Baltimore, Maryland, USA.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2020 Apr; Vol. 79 (4), pp. 525-528. Date of Electronic Publication: 2020 Feb 25.

Plasterer's tophi.

Autor: Kraines JL, Ellman MH

Publikováno v: Arthritis and rheumatism [Arthritis Rheum] 1982 Apr; Vol. 25 (4), pp. 472-3.