Onset of Efficacy Following Oral Treatment With Lasmiditan for the Acute Treatment of Migraine: Integrated Results From 2 Randomized Double-Blind Placebo-Controlled Phase 3 Clinical Studies

Autor: Cristina Tassorelli, Messoud Ashina, Kraig S. Kinchen, Leah Jin, Louise Lombard, Erin G Doty, Laura Yunes-Medina, Elizabeth Gray, Raghavendra Vasudeva

Publikováno v: Headache
Ashina, M, Vasudeva, R, Jin, L, Lombard, L, Gray, E, Doty, E G, Yunes-Medina, L, Kinchen, K S & Tassorelli, C 2019, ' Onset of Efficacy Following Oral Treatment With Lasmiditan for the Acute Treatment of Migraine : Integrated Results From 2 Randomized Double-Blind Placebo-Controlled Phase 3 Clinical Studies ', Headache, vol. 59, no. 10, pp. 1788-1801 . https://doi.org/10.1111/head.13636

OBJECTIVE To expand on available information on the efficacy of oral lasmiditan for the acute treatment of migraine with particular focus on the timing of the effect and on its impact on migraine-associated symptoms. BACKGROUND Lasmiditan is a novel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510746e2cc925e80fac8b15d036046e4
https://pubmed.ncbi.nlm.nih.gov/31529622

Psychometric testing of two new patient‐reported outcome instruments for the evaluation of treatment for hypogonadism

Autor: Kraig S. Kinchen, Xiao Ni, Darell Heiselman, Risa P. Hayes

Publikováno v: International Journal of Clinical Practice

Summary Aim The aim of this study was to perform psychometric testing and estimate minimal important change (MIC) of two new patient‐reported outcome (PRO) instruments – Sexual Arousal, Interest and Drive Scale (SAID) and Hypogonadism Energy Diar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3003a371fa4af02bbad2f099debccc
https://doi.org/10.1111/ijcp.12828

The Direct and Indirect Costs among U.S. Privately Insured Employees with Hypogonadism

Autor: Howard G. Birnbaum, Melissa Diener, Jasmina I. Ivanova, Ralph Swindle, Shonda A. Foster, Rachel Bergman, Kraig S. Kinchen, Anna Kaltenboeck

Publikováno v: The Journal of Sexual Medicine. 9:2438-2447

Introduction While previous studies have noted that hypogonadism (HG) may pose a significant economic and quality‐of‐life burden, no studies have evaluated the impact of HG on healthcare utilization and costs in the United States. Aim Compare dir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a978180a20178d23c2a72fe5f16b06ee
https://doi.org/10.1111/j.1743-6109.2012.02810.x

Effect of Testosterone Solution 2% on Testosterone Concentration, Sex Drive and Energy in Hypogonadal Men: Results of a Placebo Controlled Study

Autor: Sherie A. Dowsett, Gerald B. Brock, John McGettigan, Risa P. Hayes, Darell Heiselman, Kraig S. Kinchen, José Maria Rodríguez Vallejo, Hermann M. Behre, Xiao Ni, Jack Knorr, Sae Woong Kim, Mario Maggi

Publikováno v: The Journal of urology. 195(3)

We determined the effect of testosterone solution 2% on total testosterone level and the 2 symptoms of hypogonadism, sex drive and energy level.This was a randomized, multicenter, double-blind, placebo controlled, 16-week study to compare the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b10c926a67882375f37bd45a744c1d3
https://pubmed.ncbi.nlm.nih.gov/26498057

Prevalence, management and impact of urinary incontinence in the workplace

Autor: Barbara Sternfeld, Tammy K. Girts, Ingrid Nygaard, Kraig S. Kinchen, Gerhardt Pohl, Nancy H. Fultz

Publikováno v: Occupational Medicine. 55:552-557

Background The few prior studies of urinary symptoms in the workplace have been small investigations of women in specific occupations (e.g. nursing) or industries (e.g. pottery manufacture). In this study, the aims were to describe the prevalence, ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d3e6fd38c0acb8a15fc5b4b0d274bc
https://doi.org/10.1093/occmed/kqi152