Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kraig Abrams"'
Publikováno v:
Transplantation Direct, Vol 6, Iss 12, p e632 (2020)
Background. Complementary, marrow donor-derived peripheral blood T-lymphocyte infusions enable consistent hematopoietic engraftment in lethally irradiated dog leukocyte antigen (DLA)-haploidentical littermate recipients, but at the cost of severe gra
Externí odkaz:
https://doaj.org/article/6dce702ccfb5462a8ae632858304e965
Autor:
Peter Moore, Stephen Gottschalk, Shihong Zhang, Karan Kohli, R Graeme Black, Brian Hayes, Cassandra Miller, Mari Maeda-Whitaker, Brett Schroeder, Kraig Abrams, Bernard Seguin, Beverly Torok-Storb, Seth Pollack
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/137ea17481d3456f9ff1f51bbbbbee16
Autor:
Elizabeth Tkaczynski, Abinaya Arulselvan, John Tkaczynski, Stephen Avery, Liqing Xiao, Beverly Torok-Storb, Kraig Abrams, Narayanam V. Rao, Gregory Johnson, Thomas P. Kennedy, Mortimer Poncz, Michele P. Lambert
Publikováno v:
Blood Advances, Vol 2, Iss 7, Pp 754-761 (2018)
Abstract: Thrombocytopenia is a significant complication of chemotherapy and radiation therapy. Platelet factor 4 (PF4; CXCL4) is a negative paracrine of megakaryopoiesis. We have shown that PF4 levels are inversely related to steady-state platelet c
Externí odkaz:
https://doaj.org/article/4b85415beb2e418f91dface3b15ff817
Autor:
Mineo Iwata, David K Madtes, Kraig Abrams, Wayne J E Lamm, Robb W Glenny, Richard A Nash, Aravind Ramakrishnan, Beverly Torok-Storb
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57179 (2013)
In the current study, we used a canine model of radiation-induced lung injury to test the effect of a single i.v. infusion of 10×10(6)/kg of marrow fibroblasts on the progression of damage following 15 Gy exposure to the right lung. The fibroblasts,
Externí odkaz:
https://doaj.org/article/659c5b4ed0974033b75308977e2dd6c6
Autor:
Seth M. Pollack, Beverly Torok-Storb, Peter F. Moore, Stephen Gottschalk, Michael C. Jensen, Stanley R. Riddell, Alexander I. Salter, Bernard Seguin, Himaly Shinglot, Juliana Chi Kei Ng, Weiqing Jing, Ali Zhang, Amy B. Heimberger, Borislav A. Alexiev, Brian C. Schulte, Kraig Abrams, Brett A. Schroeder, Amanda Koehne, Cassandra Miller, Brian J. Hayes, Karan Kohli, R. Graeme Black, Shihong Zhang
One obstacle for human solid tumor immunotherapy research is the lack of clinically relevant animal models. In this study, we sought to establish a chimeric antigen receptor (CAR) T-cell treatment model for naturally occurring canine sarcomas as a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c913227bf6c523963cd395a6c7792b
https://doi.org/10.1158/1535-7163.c.6543363
https://doi.org/10.1158/1535-7163.c.6543363
Autor:
Seth M. Pollack, Beverly Torok-Storb, Peter F. Moore, Stephen Gottschalk, Michael C. Jensen, Stanley R. Riddell, Alexander I. Salter, Bernard Seguin, Himaly Shinglot, Juliana Chi Kei Ng, Weiqing Jing, Ali Zhang, Amy B. Heimberger, Borislav A. Alexiev, Brian C. Schulte, Kraig Abrams, Brett A. Schroeder, Amanda Koehne, Cassandra Miller, Brian J. Hayes, Karan Kohli, R. Graeme Black, Shihong Zhang
Supplementary Figure from B7-H3 Specific CAR T Cells for the Naturally Occurring, Spontaneous Canine Sarcoma Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a1519317178c58461723ad4240fcf4
https://doi.org/10.1158/1535-7163.22522389
https://doi.org/10.1158/1535-7163.22522389
Autor:
Shihong Zhang, R. Graeme Black, Karan Kohli, Brian J. Hayes, Cassandra Miller, Amanda Koehne, Brett A. Schroeder, Kraig Abrams, Brian C. Schulte, Borislav A. Alexiev, Amy B. Heimberger, Ali Zhang, Weiqing Jing, Juliana Chi Kei Ng, Himaly Shinglot, Bernard Seguin, Alexander I. Salter, Stanley R. Riddell, Michael C. Jensen, Stephen Gottschalk, Peter F. Moore, Beverly Torok-Storb, Seth M. Pollack
Publikováno v:
Molecular Cancer Therapeutics. 21:999-1009
One obstacle for human solid tumor immunotherapy research is the lack of clinically relevant animal models. In this study, we sought to establish a chimeric antigen receptor (CAR) T-cell treatment model for naturally occurring canine sarcomas as a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3bc34c5f130b0fb99869b2a95dd0e4
https://doi.org/10.1158/1535-7163.mct-21-0726
https://doi.org/10.1158/1535-7163.mct-21-0726
Autor:
Karan Kohli, R. Graeme Black, Kraig Abrams, Peter F Moore, Beverly Torok-Storb, Brett Schroeder, Mari Maeda-Whitaker, Stephen Gottschalk, Brian Hayes, Seth M. Pollack, Cassandra Miller, Bernard Séguin, Shihong Zhang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Chimeric antigen receptor (CAR) T cell therapy has transformed therapy for hematological malignancies but has not yet been established as standard of care for any solid tumors. One obstacle for human solid tumor immunotherapy research is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25121e1657d998cae74641a504780b21
https://doi.org/10.1136/jitc-2020-sitc2020.0139
https://doi.org/10.1136/jitc-2020-sitc2020.0139
Publikováno v:
Transplantation
BACKGROUND Chronic graft-versus-host disease (GVHD) is a significant cause of morbidity and mortality in transplant patients. We have previously shown that 3 doses of an anti-inducible costimulator (ICOS) mAb transiently ameliorated symptoms and exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c212b62245981accb0a38f2e1c1c0bcd
https://pubmed.ncbi.nlm.nih.gov/33065723
https://pubmed.ncbi.nlm.nih.gov/33065723
Autor:
Kraig Abrams, Susanna Gallo, Boglarka Gyurkocza, Marium Saad, Christoph Jochum, Diane Stone, Rainer Storb, Maura H. Parker, Steven Lawrence Rosinski, Melissa M. Johnson, Scott S. Graves
Publikováno v:
Vet Immunol Immunopathol
Natural killer (NK) cells are non-T, non-B lymphocytes are part of the innate immune system and function without prior activation. The human NK cell surface determinant, CD94, plays a critical role in regulation of NK cell activity as a heterodimer w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b0a9831929e638c76185368911d1b4
https://europepmc.org/articles/PMC7048049/
https://europepmc.org/articles/PMC7048049/