Výsledky vyhledávání - "Kraakbeenafbraak en chondrocytschade bij gewrichtsontstekingen"

Quantification of mRNA levels in joint capsule and articular cartilage of the murine knee joint by RT-PCR: Kinetics of stromelysin and IL-1 mRNA levels during arthritis

Autor: P.L.E.M. van Lent, W.B. van den Berg, Leo A. B. Joosten, J.B.J. van Meurs, P.M. van der Kraan

Publikováno v: Rheumatology International, 16, 197-205
Rheumatology International, 16, pp. 197-205

We developed a method to isolate well defined joint specimens from different compartments of normal and arthritic murine knee joints in which mRNA levels of stromelysin and IL-1 were semiquantified using RT-PCR. Joint capsule specimens were isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a896a5f82fb95d6a4b64a18639dcd0f4
https://hdl.handle.net/2066/24739

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Quantification of morphometric changes in murine experimental osteaoarthritis using image analysis

Autor: W.B. van den Berg, A. A. van Valburg, P.M. van der Kraan, G.J.V.M. van Osch

Publikováno v: Rheumatology International, 15, 181-187
Rheumatology International, 15, pp. 181-187

The aim of this study was to evaluate a method for the quantification of cartilage erosions and osteophyte sizes in a murine model of osteoarthritis (OA). Mice in which OA was induced in the knee joint by intra-articular injection of bacterial collag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0240e7c2d832d049c4ea96791b0ebe
https://hdl.handle.net/2066/22835

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Animal models of arthritis in NOS2-deficient mice

Autor: Leo A. B. Joosten, W.B. van den Berg, F.A.J. van de Loo, Onno J. Arntz

Publikováno v: Osteoarthritis and Cartilage, 7, 413-415
Osteoarthritis and Cartilage, 7, pp. 413-415

Objective To study the role of nitric oxide (NO) in cartilage destruction in murine models of arthritis and osteoarthritis. Methods Joint inflammation was induced in the knee joint by intraarticular injection of Zymosan. Osteoarthritis was induced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc1f57cf264f51560155ce4731372aa

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Denaturation of type II collagen in articular cartilage in experimental murine arthritis. Evidence for collagen degradation in both reversible and irreversible cartilage damage

Autor: A.R. Poole, W.B. van den Berg, P.M. van der Kraan, Pieter Buma, Reinout Stoop, Anthony P. Hollander

Publikováno v: Journal of Pathology, 188, 329-337
Journal of Pathology, 188, 3, pp. 329-337

Degradation of type II collagen is thought to be a key step in the destruction of articular cartilage in patients with rheumatoid arthritis or osteoarthritis. The aim of this study was to investigate whether type II collagen degradation is associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff6092b632c2162627538feeb00c937
http://hdl.handle.net/2066/165890

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Kinetics of aggrecanase and metalloproteinase induced neoepitopes in various stages of cartilage destruction in murine arthritis

Autor: Meurs, J.B.J. van, Lent, P.L.E.M. van, Holthuysen, A.E.M., Singer, M.V., Bayne, E.K., Berg, W.B. van den

Publikováno v: Arthritis and Rheumatism, 42, pp. 1128-1139
Arthritis and Rheumatism, 42, 1128-1139

Item does not contain fulltext 12 p.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::035a3f45dadf70e6756dd6808bfdc89b
https://repository.ubn.ru.nl/handle/2066/258785

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Increased vulnerability of postarthritic cartilage to a second arthritic insult: accelerated MMP activity in a flare up of arthritis

Autor: P.L.E.M. van Lent, W.B. van den Berg, J.B. van Meurs, Ellen K. Bayne, A.E.M. Holthuysen, Irwin I. Singer, A. A. J. Van De Loo

Publikováno v: Annals of the Rheumatic Diseases, 58, pp. 350-356
Annals of the Rheumatic Diseases, 58, 350-356

OBJECTIVE—Murine antigen induced arthritis (AIA) is a chronic, smouldering inflammation. Flares of arthritis can be induced by antigen rechallenge or exposure to inflammatory mediators like interleukin 1 (IL1). These flares are characterised by a f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626ced81f7c3a03c0d1d9a598677ccde
https://doi.org/10.1136/ard.58.6.350

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Articular cartilage: cause or victim in arthritis

Autor: Berg, W.B. van den

Publikováno v: Scandinavian Journal of Rheumatology, 24, 31-37
Scandinavian Journal of Rheumatology, 24, 101, pp. 31-37
Scandinavian Journal of Rheumatology, 24, (101), pp. 31-37

Item does not contain fulltext 7 p.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b1047190b1575118393218f9ab6aeff2
http://hdl.handle.net/2066/257614

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