Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD

Autor: Eg, Smet, Lj, Seys, Fm, Verhamme, Bm, Vanaudenaerde, Guy Brusselle, Cd, Bingle, Kr, Bracke

Publikováno v: International Journal of COPD, Vol Volume 13, Pp 11-27 (2017)
Europe PubMed Central

Elise G De Smet,1 Leen JM Seys,1,2 Fien M Verhamme,1 Bart M Vanaudenaerde,3 Guy G Brusselle,1 Colin D Bingle,4 Ken R Bracke1 1Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent Universit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0ac96eae7aa7e720a61c043946b2243f
https://www.dovepress.com/association-of-innate-defense-proteins-bpifa1-and-bpifb1-with-disease--peer-reviewed-article-COPD

Inflammasomes in respiratory disease: from bench to bedside

Autor: Guy Brusselle, Provoost S, Kr, Bracke, Kuchmiy A, Lamkanfi M

Publikováno v: Europe PubMed Central
Chest, 145(5), 1121-1133. American College of Chest Physicians

The respiratory tract of human subjects is constantly exposed to harmful microbes and air pollutants. The immune system responds to these offenders to protect the host, but an unbalanced inflammatory response itself may promote tissue damage and ulti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dc9d252835c290a51fc761e9c012940d
http://europepmc.org/abstract/med/24798836

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Autor: Conickx G, Mestdagh P, Avila Cobos F, Fm, Verhamme, Maes T, Bm, Vanaudenaerde, Lj, Seys, Lahousse L, Ry, Kim, Alan Hsu, Pa, Wark, Pm, Hansbro, Gf, Joos, Vandesompele J, Kr, Bracke, Gg, Brusselle

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5f4125faec94005575995eca9ad8e278
http://europepmc.org/abstract/med/27409149

Evaluating β 2 -agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy.

Autor: Merckx P; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: pieterjan.merckx@ugent.be., Conickx G; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Faculty of Medicine and Health Sciences, Department of Respiratory Medicine, Ghent University Hospital, Medical Research Building 2, Corneel Heymanslaan 10, 9000 Ghent, Belgium. Electronic address: griet.conickx@ugent.be., Blomme E; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Faculty of Medicine and Health Sciences, Department of Respiratory Medicine, Ghent University Hospital, Medical Research Building 2, Corneel Heymanslaan 10, 9000 Ghent, Belgium. Electronic address: evy.blomme@ugent.be., Maes T; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Faculty of Medicine and Health Sciences, Department of Respiratory Medicine, Ghent University Hospital, Medical Research Building 2, Corneel Heymanslaan 10, 9000 Ghent, Belgium. Electronic address: tania.maes@ugent.be., Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Faculty of Medicine and Health Sciences, Department of Respiratory Medicine, Ghent University Hospital, Medical Research Building 2, Corneel Heymanslaan 10, 9000 Ghent, Belgium. Electronic address: ken.bracke@ugent.be., Brusselle G; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Faculty of Medicine and Health Sciences, Department of Respiratory Medicine, Ghent University Hospital, Medical Research Building 2, Corneel Heymanslaan 10, 9000 Ghent, Belgium. Electronic address: guy.brusselle@ugent.be., De Smedt SC; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: stefaan.desmedt@ugent.be., Raemdonck K; Ghent Research Group on Nanomedicines, Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: koen.raemdonck@ugent.be.

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Apr; Vol. 197, pp. 114223. Date of Electronic Publication: 2024 Feb 15.

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.

Autor: Liu G; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Haw TJ; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Starkey MR; Depatrment of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, Victoria, Australia., Philp AM; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine and Health, St Vincent's Healthcare clinical campus, UNSW, Sydney, Australia., Pavlidis S; The Airways Disease Section, National Heart & Lung Institute, Imperial College London, London, UK., Nalkurthi C; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Nair PM; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Gomez HM; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Hanish I; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia.; Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia., Hsu AC; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Hortle E; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Pickles S; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Rojas-Quintero J; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA., Estepar RSJ; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA., Marshall JE; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Kim RY; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, Australia., Collison AM; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Mattes J; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Idrees S; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Faiz A; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Hansbro NG; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia., Fukui R; Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minatoku, Tokyo, Japan., Murakami Y; Faculty of Pharmacy, Department of Pharmaceutical Sciences, Musashino University, Nishitokyo-shi, Tokyo, Japan., Cheng HS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Tan NS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Chotirmall SH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore., Horvat JC; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Foster PS; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Oliver BG; Woolcock Institute of Medical Research, University of Sydney & School of Life Sciences, University of Technology, Sydney, Australia., Polverino F; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA., Ieni A; Department of Human Pathology in Adult and Developmental Age 'Gaetano Barresi', Section of Anatomic Pathology, Università di Messina, Messina, Italy., Monaco F; Thoracic Surgery, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università di Messina, Messina, Italy., Caramori G; Pneumologia, Dipartimento BIOMORF and Dipartimento di Medicina e Chirurgia, Universities of Messina and Parma, Messina, Italy., Sohal SS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, University of Tasmania, Launceston, Australia., Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Wark PA; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia., Adcock IM; School of Clinical Medicine, UNSW Medicine and Health, St Vincent's Healthcare clinical campus, UNSW, Sydney, Australia., Miyake K; Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minatoku, Tokyo, Japan., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital & Respiratory Division, Dept of Medicine, University of British Columbia, Vancouver, BC, Canada., Hansbro PM; Centre for Inflammation, Centenary Institute, and Faculty of Science, University of Technology Sydney, Camperdown, New South Wales, Australia. philip.hansbro@uts.edu.au.; Immune Healthy &/or Grow Up Well, Hunter Medical Research Institute & University of Newcastle, Callaghan, New South Wales, Australia. philip.hansbro@uts.edu.au.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 14; Vol. 14 (1), pp. 7349. Date of Electronic Publication: 2023 Nov 14.