Výsledky vyhledávání - "Kozue Toyota"

Abstract 5456: Discovery of OTS447, a highly potent and selective inhibitor of FLT3 for the treatment of AML patients with FLT3-ITD/TKD mutations

Autor: Yasuhide Okamoto, Naofumi Takamatsu, Takashi Miyamoto, Akiko Taira, Kozue Toyota, Yukiho Imai, Shinobu Fujii, Rumiko Ono, Kyoko Adachi, Yo Matsuo, Suyoun Chung, Jae-Hyun Park

Publikováno v: Cancer Research. 82:5456-5456

FMS-like tyrosine kinase 3 (FLT3) is one of the most frequently mutated genes in acute myeloid leukemia (AML), and its activating mutations including internal tandem duplications (ITDs) and missense point mutations in the tyrosine kinase domain (TKD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1948efe5b471b1af49b6c310babf9129
https://doi.org/10.1158/1538-7445.am2022-5456

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