Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kozo Yokomuro"'
Autor:
Kozo Yokomuro, Akihiko Yano, Ayako Mabuchi, Toshiyuki Ishiwata, Osamu Koshio, Kazuo Suzuki, Antony M. Wheatley, Tomokazu Nagao
Publikováno v:
Hepatology Research. 38:1040-1049
AIM Non-parenchymal liver cells (NPLC) play an important role in the regulation of immune responses and the inflammatory process. In this study, we hypothesized that F4/80(+)Mac-1(high+) cells were involved in the regulative feedback-modulated regula
Autor:
So Matui, Terutaka Kakiuchi, Kenji Kaneda, Masaki Terabe, Kozo Yokomuro, Hiroyasu Morikawa, Ayako Mabuchi, Masumi Shimizu
Publikováno v:
Hepatology. 32:507-513
We previously found that a small dose (2 μg per mouse) of staphylococcal enterotoxin B (SEB) induced early emerging unresponsiveness in intrahepatic-lymphocyte populations (IHLs). The purpose of this study was to reveal the inducing role of accessor
Publikováno v:
Immunological Investigations. 28:137-148
How the clonality of γδ T cells changes in response to exogenous antigens is uncertain. Here we analyzed kinetics of Vγ1.1 and Vγ2 T cell clonality after intraperitoneal injection of purified protein derivatives (PPD) by the heterogeneity of the
Publikováno v:
Biomedical Research. 19:135-143
Publikováno v:
Scandinavian Journal of Immunology. 46:230-234
It has been reported that the intrahepatic lymphocyte (IHL) population is somewhat differently constituted from lymphocytes in other lymphoid tissues. Staphylococcal enterotoxin B (SEB) is a superantigen which can induce T-cell tolerance in mice. The
Publikováno v:
Journal of Nippon Medical School. 64:225-231
Passive cutaneous anaphylaxis (PCA) reaction was developed by Ovary et al. as an animal model of mainly human type I allergic inflammation reaction. This is the most sensitive reaction for the detection of cutaneously sensitizing antibodies and provi
Autor:
Jun-ichi Miyazaki, Yuzo Kodaira, Kazushige Maki, Shinji Sunaga, Koichi Ikuta, Hajime Karasuyama, Yoshinori Komagata, Ayako Mabuchi, Kozo Yokomuro
Publikováno v:
Proceedings of the National Academy of Sciences. 93:7172-7177
The interleukin 7 receptor (IL-7R) plays a crucial role in early B- and T-cell development. It consists of a unique a chain and a common gamma chain [IL-2 receptor gamma chain (IL-2Rgamma)]. Gene inactivation of IL-7, IL-7R, and IL-2Rgamma resulted i
Autor:
Testuo Sudo, Kozo Yokomuro, Ayako Mabuchi, Toshiki Sakamoto, Taku Tsukui, Goro Asano, Kyoko Kikuchi
Publikováno v:
Experimental Cell Research. 210:172-176
The production of interleukin-1 (IL-1) by cultured parenchymal liver cells was revealed by a biological assay with an IL-1-dependent cell line, Northern blot analysis, and in situ hybridization. Inhibition experiments on the IL-1 activity with anti I
Publikováno v:
Journal of Nippon Medical School. 61:114-119
In the intrahepatic lymphocyte fraction (IHL) of mice whose livers have been perfused by Ca+2 and Mg+2 free Hank's balance salt solution, flow cytometric analysis reveals various cells similar to those found in the spleen (CD3+ cell, CD4+ cell, CD8+
Publikováno v:
Journal of Nippon Medical School. 61:26-35
Since sinusoidal liver cells directly interact with circulating hemopoietic cells and lymphocytes, Kupffer cells may have the capacity to trap and activate these cells in the liver microcirculation. In order to investigate the adhesion mechanism of K