Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Kozo Ochi"'
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232927 (2020)
Tetraene macrolides remain one of the most reliable fungicidal agents as resistance of fungal pathogens to these antibiotics is relatively rare. The modes of action and biosynthesis of polyene macrolides had been the focus of research over the past f
Externí odkaz:
https://doaj.org/article/c3d83ec713b04e0ba1db6a50dbc226cd
Tri11, tri3, and tri4 genes are required for trichodermin biosynthesis of Trichoderma brevicompactum
Publikováno v:
AMB Express, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Trichoderma brevicompactum and T. arundinaceum both can synthesize trichodermin with strong antifungal activity and high biotechnological value. The two Trichoderma species have a tri cluster, which includes seven genes (tri14, tri12, tri11,
Externí odkaz:
https://doaj.org/article/c93de255f6ed4abd97eb7271686dfd9f
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203006 (2018)
Toyocamycin is a member of the nucleoside antibiotic family and has been recognized as a promising fungicide for the control of plant diseases. However, low productivity of toyocamycin remains an important bottleneck in its industrial production. The
Externí odkaz:
https://doaj.org/article/bf37f4ae70f141c9879502ceb43d4c47
Autor:
Vasylyna-Marta Tseduliak, Borys Dolia, Iryna Ostash, Maria Lopatniuk, Tobias Busche, Kozo Ochi, Jörn Kalinowski, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Publikováno v:
Journal of applied genetics.
Streptomyces albus J1074 is one of the most popular heterologous expression platforms among streptomycetes. Identification of new genes and mutations that influence specialized metabolism in this species is therefore of great applied interest. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bb1f9ed0a9bdd4a4118a1a1a350ccb
https://pubmed.ncbi.nlm.nih.gov/36417169
https://pubmed.ncbi.nlm.nih.gov/36417169
Autor:
Bohdan Ostash, Victor Fedorenko, Kozo Ochi, Oksana Borys, Volodymyr Kravets, Andriy Luzhetskyy, Anastasiia Shemediuk, Yuya Misaki, Iryna Ostash, Oksana Koshla, Maria Lopatniuk
Publikováno v:
World Journal of Microbiology and Biotechnology. 37
Certain point mutations within gene for ribosomal protein S12, rpsL, are known to dramatically change physiological traits of bacteria, most prominently antibiotic resistance and production of various metabolites. The rpsL mutants are usually searche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb9060d38f9f368712118a430213981
https://doi.org/10.1007/s11274-021-03030-5
https://doi.org/10.1007/s11274-021-03030-5
Autor:
Michio Yamamoto, Michiko Nemoto, Kenji Inagaki, Toshiyuki Hirano, Saori Ogawa, Hiroyuki Ogata, Hitomi Shimidzu, Kozo Ochi, Wataru Sakamoto, Tadayoshi Kanao, Kei Yura, Koji Fukuda, Tomohisa Hasunuma, Naoki Tsunekawa, Takashi Tamura, Kentaro Hashimoto, Fumitoshi Sato
Publikováno v:
Bioscience, biotechnology, and biochemistry. 85(5)
Streptomyces incarnatus NRRL8089 produces the antiviral, antifungal, antiprotozoal nucleoside antibiotic sinefungin. To enhance sinefungin production, multiple mutations were introduced to the rpoB gene encoding RNA polymerase (RNAP) β-subunit at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49cdce3131fa5135b997fd375bc620e
https://pubmed.ncbi.nlm.nih.gov/33710298
https://pubmed.ncbi.nlm.nih.gov/33710298
Tri11, tri3, and tri4 genes are required for trichodermin biosynthesis of Trichoderma brevicompactum
Publikováno v:
AMB Express, Vol 8, Iss 1, Pp 1-11 (2018)
AMB Express
AMB Express
Trichoderma brevicompactum and T. arundinaceum both can synthesize trichodermin with strong antifungal activity and high biotechnological value. The two Trichoderma species have a tri cluster, which includes seven genes (tri14, tri12, tri11, tri10, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9640529116ae8903d06ee1f23ecaaf86
http://link.springer.com/article/10.1186/s13568-018-0585-4
http://link.springer.com/article/10.1186/s13568-018-0585-4
Autor:
Yu Imai, Kozo Ochi, Keiichiro Mukai, Kazuma Shimono, Misaki Ishizuka, Takeshi Hosaka, Ryoko Hamauzu
Publikováno v:
Antonie van Leeuwenhoek. 111:705-716
Lincomycin forms cross-links within the peptidyl transferase loop region of the 23S ribosomal RNA (rRNA) of the 50S subunit of the bacterial ribosome, which is the site of peptide bond formation, thereby inhibiting protein synthesis. We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76b4b8ff571aa4eda6fe1a33972206f
https://doi.org/10.1007/s10482-018-1021-0
https://doi.org/10.1007/s10482-018-1021-0
Publikováno v:
Journal of Bioscience and Bioengineering. 124:400-407
Ribosome engineering, originally applied to Streptomyces lividans, has been widely utilized for strain improvement, especially for the activation of bacterial secondary metabolism. This study assessed ribosome engineering technology to modulate prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1c2641089eecfeafd696a07928124e
https://doi.org/10.1016/j.jbiosc.2017.05.003
https://doi.org/10.1016/j.jbiosc.2017.05.003
Publikováno v:
Applied Microbiology and Biotechnology. 101:4417-4431
Although transcriptional activation of pathwayspecific positive regulatory genes and/or biosynthetic genes is primarily important for enhancing secondary metabolite production, reinforcement of substrate supply, as represented by primary metabolites,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9920d64bd3ae63cdeb9d7d329fa1875c
https://doi.org/10.1007/s00253-017-8216-6
https://doi.org/10.1007/s00253-017-8216-6