Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kozo Shaura"'
Autor:
Tomoyuki Hanaoka, Kozo Shaura, Tetsuya Otani, Teruhiko Yoshida, Shoichiro Tsugane, Junko Ishihara, Yoichi Koizumi, Kimio Yoshimura, Motoki Iwasaki, Syusuke Natsukawa, Minatsu Kobayashi, Yoshio Kasuga
Publikováno v:
Nutrition and Cancer. 53:42-50
We conducted a case-control study to investigate the association of nutrient intake involved in the one-carbon pathway of folate for DNA methylation and DNA synthesis and the related enzyme genetic polymorphisms with colorectal cancer. Cases were 107
Autor:
Kozo Shaura, Motoki Iwasaki, Tomoyuki Hanaoka, Megumi Hara, Yoichi Koizumi, Shoichiro Tsugane, Hiromasa Tsukino, Syusuke Natsukawa, Minatsu Kobayashi, Tetsuya Otani, Yoshio Kasuga
Publikováno v:
Cancer Science. 95:977-983
Oxidative DNA damage caused by reactive oxygen species (ROS) generated by Helicobacter pylori (H. pylori) infection or smoking may be a cause of gastric cancer development. 8-Hydroxydeoxyguanine (8-OHdG) formation is one of the most common types of o
Autor:
Syusuke Natsukawa, Ai Machida-Montani, Shoichiro Tsugane, Manami Inoue, Tomoyuki Hanaoka, Yoichi Koizumi, Shizuka Sasazuki, Yoshio Kasuga, Kozo Shaura
Publikováno v:
Gastric Cancer. 7:46-53
Although Helicobacter pylori infection is a major risk factor for gastric cancer, it does not explain the full picture of stomach carcinogenesis. There have been few epidemiological studies, however, which examined both H. pylori and environmental fa
Autor:
Helena Yukari Adachi, Minatsu Kobayashi, Tomoyuki Hanaoka, Yoichi Koizumi, Tetsuya Otani, Shoichiro Tsugane, Tsunetomo Matsuzawa, Megumi Hara, Syusuke Natsukawa, Kozo Shaura, Ai Montani, Yoshio Kasuga, Satoshi Sasaki, Tetsuro Ikekawa
Publikováno v:
Scopus-Elsevier
We assessed the possible association of gastrointestinal cancers with cruciferous vegetables and mushrooms in a multicenter, hospital-based case-control study in an agricultural area of Japan. One hundred forty-nine cases and 287 controls for stomach
Autor:
Kenji Usui, Ken Kusano, Akira Oka, Masaki Numata, Sachihiko Yamase, Zenji Shimizu, Yasuo Chuman, Kozo Shaura
Publikováno v:
JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE. 42:16-23
長野県厚生連における胃集検のコンピューターによる精度管理と読影モデルを用いた読影テストについて報告した。正常例30例, 胃癌症例20例よりなる読影モデルと読影者の判定したグレ
Autor:
Minatsu Kobayashi, Shoichiro Tsugane, Shusuke Natsukawa, Motoki Iwasaki, Yoshio Kasuga, Hiromi Sakamoto, Yoichi Koizumi, Tetsuya Otani, Teruhiko Yoshida, Kozo Shaura
Publikováno v:
Scandinavian journal of gastroenterology. 44(8)
Although associations between dietary HCA intake and colorectal cancer risk have been investigated, results have been suggestive but inconsistent. The aim of this hospital-based case-control study was to examine the impact of heterocyclic amine (HCA)
Autor:
Shusuke Natsukawa, Hiromi Sakamoto, Yoichi Koizumi, Motoki Iwasaki, Teruhiko Yoshida, Kozo Shaura, Tetsuya Otani, Yoshio Kasuga, Shoichiro Tsugane, Minatsu Kobayashi
Publikováno v:
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 12(4)
Although the associations between grilled (broiled) or barbecued meats or fish intake and stomach cancer risk have been investigated, the evidence implicating heterocyclic amine (HCA) intake as a cause of stomach cancer is limited. We conducted a cas
Autor:
Motoki Iwasaki, Yoshio Kasuga, Syusuke Natsukawa, Shoichiro Tsugane, Sumiko Ohnami, Shinobu Ikeda, Hiromi Sakamoto, Shizuka Sasazuki, Yoichi Koizumi, Teruhiko Yoshida, Kozo Shaura
Publikováno v:
The American journal of gastroenterology. 103(6)
Single nucleotide polymorphisms (SNPs) have potential as markers for identifying genes responsible for common diseases and for personalized medicine. To investigate the association between polymorphisms and gastrointestinal (gastric and colorectal) c
Autor:
Tomoyuki Hanaoka, Ai Machida-Montani, Yoichi Koizumi, Kozo Shaura, Syusuke Natsukawa, Shoichiro Tsugane, Shizuka Sasazuki, Manami Inoue, Yoshio Kasuga
Publikováno v:
Helicobacter. 12(4)
Background: Helicobacter pylori is a major risk factor for atrophic gastritis and gastric cancer. Various extragastric manifestations of H. pylori infection have also recently been suggested. However, the correlation between H. pylori and colorectal
Autor:
Tomoyuki Hanaoka, Yoichi Koizumi, Syusuke Natsukawa, Hong Tao, Takachika Ozawa, Kazuya Shinmura, Satoru Yamaguchi, Zhong-You Li, Haruhiko Sugimura, Jun Yokota, Yoshio Kasuga, Shoichiro Tsugane, Toshimasa Tsujinaka, Kozo Shaura
Publikováno v:
Carcinogenesis. 25(10)
The MYH gene encodes a DNA glycosylase involved in the excision repair of adenines paired with 8-hydroxyguanines, a major component of oxidative DNA damage, and bi-allelic germline MYH mutations have been reported to predispose individuals to multipl