Zobrazeno 1 - 10
of 351
pro vyhledávání: '"Kozo, Takayama"'
Autor:
Shoko Itakura, Ayaka Shohji, Sayaka Amagai, Masashi Kitamura, Kozo Takayama, Kenji Sugibayashi, Hiroaki Todo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Small interfering RNAs (siRNAs) knockdown the expression of target genes by causing mRNA degradation and are a promising therapeutic modality. In clinical practice, lipid nanoparticles (LNPs) are used to deliver RNAs, such as siRNA and mRNA,
Externí odkaz:
https://doaj.org/article/f96df1de8724498eadfc95c6b189c627
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:386-397
Autor:
Sureewan Duangjit, Phaijit Sritananuwat, Sureewan Bumrungthai, Tanasait Ngawhirunpat, Kozo Takayama
Publikováno v:
Cosmetics, Vol 9, Iss 5, p 104 (2022)
Coronavirus disease (COVID-19) cases are continuing to rise around the world, with more than 607 million confirmed cases and more than 6.51 million deaths as of September 2022. The World Health Organization (WHO) has emphasized the importance of hygi
Externí odkaz:
https://doaj.org/article/0cc53dbfc3714bf2bb252635200bf6eb
Autor:
Shoko Itakura, Ayaka Shohji, Sayaka Amagai, Masashi Kitamura, Kozo Takayama, Kenji Sugibayashi, Hiroaki Todo
Small interfering RNAs (siRNAs) knockdown the expression of target genes by causing mRNA degradation and are a promising therapeutic modality. In clinical practice, lipid nanoparticles (LNPs) are used to deliver RNAs, such as siRNA and mRNA, into cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf6d2d787378076394e585796aa2a53
https://doi.org/10.21203/rs.3.rs-2189478/v1
https://doi.org/10.21203/rs.3.rs-2189478/v1
Autor:
Kenji Sugibayashi, Yuya Yoshida, Ryuichiro Suzuki, Kota Yoshizawa, Kenji Mori, Shoko Itakura, Kozo Takayama, Hiroaki Todo
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 427 (2020)
A highly viscous substance was prepared by evaporating an ethanol solution containing two hydrophilic vitamins; vitamin C, and vitamin B6. The viscous substance and physical mixture of the two vitamins were tested using a differential scanning calori
Externí odkaz:
https://doaj.org/article/bc42169797e24378889a7429a1625b2b
Publikováno v:
Powder Technology. 383:115-130
Scored tablets are produced to facilitate easy and uniform division of tablets. One of the most critical quality attributes of the scored tablet is its dividing uniformity. To clarify the tablet dividing mechanism, we proposed a novel algorithm on th
Autor:
Siew Hwei Yap, Noor Kamila Abdullah, Megan McStea, Kozo Takayama, Meng Li Chong, Elisa Crisci, Marie Larsson, Iskandar Azwa, Adeeba Kamarulzaman, Kok Hoong Leong, Yin Ling Woo, Reena Rajasuriar
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186000 (2017)
Co-infections with human herpesvirus (HHV) have been associated with residual chronic inflammation in antiretroviral (ART)-treated human immunodeficiency virus (HIV)-infected individuals. However, the role of HHV in modulating the tryptophan-kynureni
Externí odkaz:
https://doaj.org/article/5d868609c1df4cc38f3424d7ee84bb92
Autor:
Asami Mogi, Tsubasa Sato, Kozo Takayama, Hiroki Katayama, Shoko Itakura, Yoshiharu Maeda, Kenji Sugibayashi, Hiroaki Todo
Publikováno v:
Chemicalpharmaceutical bulletin. 69(11)
From the viewpoint of self-medication, it is valuable to develop patient-friendly scored tablets that possess dividing uniformity. In this context, we attempted to optimize the preparation conditions for a tablet with a unique shape, such as a concav
Latent Structure Analysis of Wet-Granulation Tableting Process Based on Structural Equation Modeling
Publikováno v:
Chemicalpharmaceutical bulletin. 69(7)
Quality by design (QbD) is an essential concept for modern manufacturing processes of pharmaceutical products. Understanding the science behind manufacturing processes is crucial; however, the complexity of the manufacturing processes makes implement
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:1144-1151
Definitive screening design (DSD) is a new class of small three-level experimental design that is attracting much attention as a technical tool of a quality by design (QbD) approach. The purpose of this study is to examine the usefulness of DSD for Q