FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity.

Autor: Hubbard JJ; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA., Pyzik M; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Rath T; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Kozicky LK; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Sand KMK; Department of Biosciences, Centre for Immune Regulation, University of Oslo, Oslo, Norway.; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway., Gandhi AK; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Grevys A; Department of Biosciences, Centre for Immune Regulation, University of Oslo, Oslo, Norway.; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway., Foss S; Department of Biosciences, Centre for Immune Regulation, University of Oslo, Oslo, Norway.; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway., Menzies SC; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Glickman JN; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA., Fiebiger E; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA., Roopenian DC; The Jackson Laboratory, Bar Harbor, ME., Sandlie I; Department of Biosciences, Centre for Immune Regulation, University of Oslo, Oslo, Norway.; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway., Andersen JT; Department of Biosciences, Centre for Immune Regulation, University of Oslo, Oslo, Norway.; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway., Sly LM; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Baker K; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Blumberg RS; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Harvard Digestive Diseases Center, Boston, MA.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2020 Oct 05; Vol. 217 (10).

Blockade of the mitochondrial DNA release ameliorates hepatic ischemia-reperfusion injury through avoiding the activation of cGAS-Sting pathway.

Autor: Xiong, Yi¹ (AUTHOR), Chen, Jiawen¹ (AUTHOR), Liang, Wei¹ (AUTHOR), Li, Kun² (AUTHOR), Huang, Yingqi¹ (AUTHOR), Song, Jingwen¹ (AUTHOR), Zhang, Baoyu³ (AUTHOR), Qiu, Xiusheng⁴ (AUTHOR), Qiu, Dongbo⁴ (AUTHOR) qiudb3@mail.sysu.edu.cn, Zhang, Qi^1,4 (AUTHOR) keekee77@126.com, Qin, Yunfei^1,4 (AUTHOR) qinyf6@mail.sysu.edu.cn

Publikováno v: Journal of Translational Medicine. 8/28/2024, Vol. 22 Issue 1, p1-16. 16p.

Depletion and Reconstitution of Macrophages in Mice.

Autor: Kozicky LK; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada., Sly LM; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada. laurasly@mail.ubc.ca.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1960, pp. 101-112.

Vaccine protection of the mother, the fetus, neonates and infants.

Autor: Wallace, Madison L.¹, Rosenthal, Ken S.^1,2,3 kenneth.rosenthal@uga.edu

Publikováno v: AIMS Allergy & Immunology. 2024, Vol. 8 Issue 2, p124-145. 22p.

Non-specific irreversible ⁸⁹Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using ⁸⁹Zr-immuno-PET.

Autor: Wijngaarden, Jessica E.^1,2 (AUTHOR) j.e.wijngaarden@amsterdamumc.nl, Jauw, Yvonne W. S.^1,2,3 (AUTHOR), Zwezerijnen, Gerben J. C.^1,2 (AUTHOR), de Wit-van der Veen, Berlinda J.⁴ (AUTHOR), Vugts, Daniëlle J.^1,2 (AUTHOR), Zijlstra, Josée M.³ (AUTHOR), van Dongen, Guus A. M. S.^1,2 (AUTHOR), Boellaard, Ronald^1,2 (AUTHOR), Menke-van der Houven van Oordt, C. Willemien⁵ (AUTHOR), Huisman, Marc C.^1,2 (AUTHOR)

Publikováno v: EJNMMI Research. 2/15/2024, Vol. 14, p1-9. 9p.