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pro vyhledávání: '"Koyuki Fukumoto"'
Autor:
Koyuki Fukumoto, Soyoung Park, Ji Hye Yum, Takumi Ishizuka, Hong-Liang Bao, Yan Xu, Hiroshi Sugiyama, Daisuke Hori
Publikováno v:
ACS Biomaterials Science & Engineering. 7(4):1338-1343
Chemical modifications of innate DNA/RNA aptamers facilitate the improvement of their function. Herein, we report our modular strategy to manipulate a thrombin-binding DNA aptamer (TBA) to improve its anticoagulation activity and binding affinity. A