Gain in 1q is a Common Abnormality in Phyllodes Tumours of the Breast

Autor: Kowan J. Jee, Gyungyub Gong, Sei Hyun Ahn, Jeong Mi Park, Sakari Knuutila

Publikováno v: Analytical Cellular Pathology, Vol 25, Iss 2, Pp 89-93 (2003)

We studied DNA copy number changes by CGH and allelic imbalance (AI) on 3p by LOH analysis on 22 phyllodes tumours (PT) of the breast in order to gain insight into the genetic basis of tumour progression in PT. Copy number changes were observed in 14

Externí odkaz: https://doaj.org/article/9c12b29d8541463dbc963436e2e07b65

Array comparative genomic hybridization identifies a distinct DNA copy number profile in renal cell cancer associated with hereditary leiomyomatosis and renal cell cancer

Autor: Rainer Lehtonen, Lauri A. Aaltonen, Virpi Launonen, Taru A. Koski, Heli J. Lehtonen, Pia Vahteristo, Kowan J. Jee, Simon A. Joosse, Marja Hietala, Kristiina Aittomäki, Sakari Knuutila, Maija Ht Kiuru, Heli Sammalkorpi, Auli Karhu, Shinsuke Ninomiya, Riitta Herva, Sakari Vanharanta, Petra M. Nederlof, Henrik Edgren

Publikováno v: Koski, T A, Lehtonen, H J, Jee, K J, Ninomiya, S, Joosse, S A, Vahteristo, P, Kiuru, M, Karhu, A, Sammalkorpi, H, Vanharanta, S, Lehtonen, R, Edgren, H, Nederlof, P M, Hietala, M, Aittomäki, K, Herva, R, Knuutila, S, Aaltonen, L A & Launonen, V 2009, ' Array comparative genomic hybridization identifies a distinct DNA copy number profile in renal cell cancer associated with hereditary leiomyomatosis and renal cell cancer ', Genes, Chromosomes and Cancer, vol. 48, no. 7, pp. 544-551 . https://doi.org/10.1002/gcc.20663

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a tumor predisposition syndrome with cutaneous and uterine leiomyomatosis as well as renal cell cancer (RCC) as its clinical manifestations. HLRCC is caused by heterozygous germline mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8996214543fff11945ba6fb7f20f3dd9
https://doi.org/10.1002/gcc.20663

Oncocytic papillary renal cell carcinoma with inverted nuclear pattern: distinct subtype with an indolent clinical course

Autor: Gyungyub Gong, Jae Y. Ro, Yong Mee Cho, Kowan J. Jee, Bong Hee Park, Won Seo Park, Kyungeun Kim

Publikováno v: Pathology international. 59(3)

Reported herein are seven cases of a histologically distinct oncocytic papillary renal cell carcinoma (OPRCC) with an inverted nuclear pattern. To define its prognostic significance, the clinicopathological features of OPRCC were compared to those of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a85f4e6babeb51a17bf53616fd0bfc
https://pubmed.ncbi.nlm.nih.gov/19261090

Loss in 3p and 4p and gain of 3q are concomitant aberrations in squamous cell carcinoma of the vulva

Autor: Sakari Knuutila, Young-Tak Kim, Kyu Rae Kim, Aalto Yan, Hy Sook Kim, Kowan J Jee

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 14(5)

Neoplasm of the vulva is a rare malignancy accounting for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ecfb682a365ba2939f76dab681de6e
https://pubmed.ncbi.nlm.nih.gov/11353045