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Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.

Autor: Nasello C; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854.; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854., Poppi LA; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854.; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854.; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Wu J; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854.; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Kowalski TF; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854.; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Thackray JK; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854.; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854., Wang R; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854.; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854., Persaud A; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854.; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Mahboob M; Department of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School and Rutgers Biomedical and Health Sciences, Newark, NJ 07103., Lin S; Department of Neurobiology, Harvard Medical School, Boston, MA 02115., Spaseska R; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854., Johnson CK; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854., Gordon D; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854., Tissir F; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha 34110, Qatar.; Laboratory of Developmental Neurobiology, Institute of Neuroscience, Université Catholique de Louvain, Brussels 1200, Belgium., Heiman GA; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854., Tischfield JA; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854., Bocarsly M; Department of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School and Rutgers Biomedical and Health Sciences, Newark, NJ 07103., Tischfield MA; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854.; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08901.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 07; Vol. 121 (19), pp. e2307156121. Date of Electronic Publication: 2024 Apr 29.

Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.

Autor: Nasello C, Poppi LA, Wu J, Kowalski TF, Thackray JK, Wang R, Persaud A, Mahboob M, Lin S, Spaseska R, Johnson CK, Gordon D, Tissir F, Heiman GA, Tischfield JA, Bocarsly M, Tischfield MA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 28. Date of Electronic Publication: 2023 Nov 28.