Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Koval Smith"'
Autor:
Leila Mekkaoui, Jose G. Tejerizo, Sara Abreu, Lydie Rubat, Aleksandra Nikoniuk, William Macmorland, Claire Horlock, Sofia Matsumoto, Sarah Williams, Koval Smith, Juliet Price, Saket Srivastava, Rehan Hussain, Mohammad Amin Banani, William Day, Elena Stevenson, Meghan Madigan, Jie Chen, Ravin Khinder, Shahed Miah, Simon Walker, Michael Ade-Onojobi, Sabine Domining, James Sillibourne, Marianna Sabatino, Vladimir Slepushkin, Farzin Farzaneh, Martin Pule
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 116-128 (2023)
γ-Retroviral vectors (γ-RV) are powerful tools for gene therapy applications. Current clinical vectors are produced from stable producer cell lines which require minimal further downstream processing, while purification schemes for γ-RV produced b
Externí odkaz:
https://doaj.org/article/c3cb671a0496433383c9625ae6699248
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
T cells are known to be plastic and to change their phenotype according to the cellular and biochemical milieu they are embedded in. In this study we transposed this concept at a macroscopic level assessing whether changes in the environmental housin
Externí odkaz:
https://doaj.org/article/922852325d35442899189c6cd597a468
Autor:
Golzar Mobayen, Koval Smith, Kushani Ediriwickrema, Richard D. Starke, Emmanouil Georgios Solomonidis, Michael A. Laffan, Anna M. Randi, Thomas A.J. McKinnon
BACKGROUND: The von Willebrand factor (VWF) is a multimeric plasma glycoprotein essential for hemostasis, inflammation, and angiogenesis. The majority of VWF is synthesized by endothelial cells (ECs) and stored in Weibel-Palade bodies (WPB). Among th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2b73f70472e4f24171978e34607f3a
http://hdl.handle.net/10044/1/104704
http://hdl.handle.net/10044/1/104704
Autor:
Nushmia Z. Khokhar, Denise Bonney, Paul Virgo, Saket Srivastava, Simon Thomas, Ram Jha, Jan Chu, Shaun Cordoba, Robert Chiesa, Persis Amrolia, Yiyun Zhang, Jeremy Hancock, Rachael Hough, Carlotta Peticone, Shimobi Onuoha, Kanchan Rao, Vania Baldan, Kevin Duffy, Paul Veys, Lucy Wheeler, Robert Wynn, William Day, Daniela Soriano Pignataro, Sara Ghorashian, Giovanna Lucchini, Koval Smith, Martin Pule, Liz Clark, Vijay G R Peddareddigari, Mathieu Ferrari, Sabine Domning, Ajay Vora, Frederick Arce Vargas, Muhammad Al-Hajj, Mei Mei Fung, Farzin Farzaneh
Publikováno v:
Nature Medicine
Chimeric antigen receptor (CAR) T cells targeting CD19 or CD22 have shown remarkable activity in B cell acute lymphoblastic leukemia (B-ALL). The major cause of treatment failure is antigen downregulation or loss. Dual antigen targeting could potenti
Autor:
Leila Mekkaoui, Jose G. Tejerizo, Sara Abreu, Lydie Rubat, Aleksandra Nikoniuk, William Macmorland, Claire Horlock, Sofia Matsumoto, Sarah Williams, Koval Smith, Juliet Price, Saket Srivastava, Rehan Hussain, Mohammad Amin Banani, William Day, Elena Stevenson, Meghan Madigan, Jie Chen, Ravin Khinder, Shahed Miah, Simon Walker, Michael Ade-Onojobi, Sabine Domining, James Sillibourne, Marianna Sabatino, Vladimir Slepushkin, Farzin Farzaneh, Martin Pule
Publikováno v:
Molecular therapy. Methodsclinical development. 28
γ-Retroviral vectors (γ-RV) are powerful tools for gene therapy applications. Current clinical vectors are produced from stable producer cell lines which require minimal further downstream processing, while purification schemes for γ-RV produced b