Výsledky vyhledávání - "Koutsoumpli, G. E."

Synthesis and Study of 2-(Pyrrolesulfonylmethyl)-N-arylimines: A New Class of Inhibitors for Human Glutathione Transferase A1-1

Autor: Koutsoumpli, G. E., Dimaki, V. D., Thireou, T. N., Eliopoulos, E. E., Labrou, N. E., Varvounis, G. I., Conis, Y. D.

Overexpression of human GSTA1-1 in tumor cells is part of MDR mechanisms. We report on the synthesis of 11 pyrrole derivatives as hGSTA1-1 inhibitors starting from 1-methyl-2-[(2-nitrobenzylsulfanyl]-1H-pyrrole. Molecular modeling revealed two locati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::75f41936e1ce2a42d90c782c348df456
http://olympias.lib.uoi.gr/jspui/handle/123456789/9438

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