Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Koutarou D. Kimura"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Recent advances in microscopy techniques, especially in electron microscopy, are transforming biomedical studies by acquiring large quantities of high-precision 3D cell image stacks. To examine cell morphology and connectivity in organs such
Externí odkaz:
https://doaj.org/article/d1e31efe06444b08b07d3a48a5980a43
Autor:
Takuya Maekawa, Daiki Higashide, Takahiro Hara, Kentarou Matsumura, Kaoru Ide, Takahisa Miyatake, Koutarou D. Kimura, Susumu Takahashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Comparing changes in behaviour across various species is not always trivial, especial across significantly divergent species. Here, the authors develop a deep learning framework that allows them to map changes in locomotion demonstrated on dopamine-d
Externí odkaz:
https://doaj.org/article/911657e57a84400da94bf27d5bd462da
Autor:
Takuya Maekawa, Kazuya Ohara, Yizhe Zhang, Matasaburo Fukutomi, Sakiko Matsumoto, Kentarou Matsumura, Hisashi Shidara, Shuhei J. Yamazaki, Ryusuke Fujisawa, Kaoru Ide, Naohisa Nagaya, Koji Yamazaki, Shinsuke Koike, Takahisa Miyatake, Koutarou D. Kimura, Hiroto Ogawa, Susumu Takahashi, Ken Yoda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Comparative analysis of animal behaviour using locomotion data such as GPS data is difficult because the large amount of data makes it difficult to contrast group differences. Here the authors apply deep learning to detect and highlight trajectories
Externí odkaz:
https://doaj.org/article/a6fc41cd07034a559224fe04d3413b43
Autor:
Shuhei J. Yamazaki, Kazuya Ohara, Kentaro Ito, Nobuo Kokubun, Takuma Kitanishi, Daisuke Takaichi, Yasufumi Yamada, Yosuke Ikejiri, Fumie Hiramatsu, Kosuke Fujita, Yuki Tanimoto, Akiko Yamazoe-Umemoto, Koichi Hashimoto, Katsufumi Sato, Ken Yoda, Akinori Takahashi, Yuki Ishikawa, Azusa Kamikouchi, Shizuko Hiryu, Takuya Maekawa, Koutarou D. Kimura
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Animal behavior is the final and integrated output of brain activity. Thus, recording and analyzing behavior is critical to understand the underlying brain function. While recording animal behavior has become easier than ever with the development of
Externí odkaz:
https://doaj.org/article/cdf98be2995541538ba5a0cf7dfe16c8
Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function
Autor:
Mami Matsumoto, Katsuyoshi Matsushita, Masaya Hane, Chentao Wen, Chihiro Kurematsu, Haruko Ota, Huy Bang Nguyen, Truc Quynh Thai, Vicente Herranz-Pérez, Masato Sawada, Koichi Fujimoto, José Manuel García-Verdugo, Koutarou D Kimura, Tatsunori Seki, Chihiro Sato, Nobuhiko Ohno, Kazunobu Sawamoto
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1228-1253 (2024)
Abstract In the injured brain, new neurons produced from endogenous neural stem cells form chains and migrate to injured areas and contribute to the regeneration of lost neurons. However, this endogenous regenerative capacity of the brain has not yet
Externí odkaz:
https://doaj.org/article/38a75c2192bc4cdea63491e9304280eb
Autor:
Yosuke Ikejiri, Yuki Tanimoto, Kosuke Fujita, Fumie Hiramatsu, Shuhei J. Yamazaki, Yuto Endo, Yasushi Iwatani, Koichi Fujimoto, Koutarou D. Kimura
Publikováno v:
Neuroscience Research
Animals’ sensory systems adjust their responsiveness to environmental stimuli that vary greatly in their intensity. Here we report the neural mechanism of experience-dependent sensory adjustment, especially gain control, in the ASH nociceptive neur
Publikováno v:
ACS Synthetic Biology. 12:700-708
Autor:
Chentao Wen, Takuya Miura, Venkatakaushik Voleti, Kazushi Yamaguchi, Motosuke Tsutsumi, Kei Yamamoto, Kohei Otomo, Yukako Fujie, Takayuki Teramoto, Takeshi Ishihara, Kazuhiro Aoki, Tomomi Nemoto, Elizabeth MC Hillman, Koutarou D Kimura
Publikováno v:
eLife, Vol 10 (2021)
Despite recent improvements in microscope technologies, segmenting and tracking cells in three-dimensional time-lapse images (3D + T images) to extract their dynamic positions and activities remains a considerable bottleneck in the field. We develope
Externí odkaz:
https://doaj.org/article/798a037c858b49c6b741110877257a1d
Recent advances in microscopy techniques, especially in electron microscopy, are transforming biomedical studies by acquiring large quantities of high-precision 3D cell image stacks. To examine cell morphology and connectivity in organs such as the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04dbc084781ca0d220ef4459765e51e7
https://doi.org/10.1101/2022.10.10.511670
https://doi.org/10.1101/2022.10.10.511670
Optogenetic techniques have been intensively applied to the nematode Caenorhabditis elegans to investigate its neural functions. However, as most of these optogenetics are responsive to blue light and the animals exhibits avoidance behavior to blue l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0a94a6ddb1b15d13d900aa8812bb52
https://doi.org/10.1101/2022.08.12.503710
https://doi.org/10.1101/2022.08.12.503710