Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kousuke Mihara"'
Autor:
Haruko Sakurama, Shigenobu Kishino, Kousuke Mihara, Akinori Ando, Keiko Kita, Satomi Takahashi, Sakayu Shimizu, Jun Ogawa
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 9, Pp 1855-1863 (2014)
The PUFAs include many bioactive lipids. The microbial metabolism of C18 PUFAs is known to produce their bioactive isomers, such as conjugated FAs and hydroxy FAs, but there is little information on that of C20 PUFAs. In this study, we aimed to obtai
Externí odkaz:
https://doaj.org/article/f6b9afcfc4be4f429b68be5d10da7dde
Autor:
Takeshi Tsumuraya, Daisuke Fujiwara, Kousuke Mihara, Ryo Takayama, Yusuke Nakamura, Ikuo Fujii, Mitsuhiro Ueda
Publikováno v:
ChemBioChem. 22:3406-3409
Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target-focused library could be a promising approach for the generation of de novo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec41844e7aef70481dd6ddb8a392ebd0
https://doi.org/10.1002/cbic.202100450
https://doi.org/10.1002/cbic.202100450
Publikováno v:
Peptide Science. 114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1ef8f344089e7a83a76f44c12f3fcd7
https://doi.org/10.1002/pep2.24253
https://doi.org/10.1002/pep2.24253
Autor:
Hidenori Mikamiyama, Taichi Ueda, Douglas R. Cary, Takashi Ono, Shota Uehara, Saki Yamamoto, Kyohei Hayashi, Junichi Nishikawa, Kousuke Mihara, Norito Yoshimura, Taeko Kawai, Shiho Yamamoto, Hiroki Ozasa, Masataka Fumoto
Publikováno v:
ACS Med Chem Lett
[Image: see text] Nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide, is a cytosolic enzyme that has attracted much attention as a therapeutic target for a variety of diseases. However, despite the considerable i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bba1edf2b98ca3892e4c8581b120f6
https://pubmed.ncbi.nlm.nih.gov/34267879
https://pubmed.ncbi.nlm.nih.gov/34267879
Publikováno v:
Applied microbiology and biotechnology. 101(17)
Maltol derivatives are utilized in a variety of fields due to their metal-chelating abilities, and modification of the 2-methyl side chain is known to effectively expand their functional diversity. In the present study, microbial enzymes were screene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772e5754a0c34725ff174d04ab4e5f42
https://pubmed.ncbi.nlm.nih.gov/28730410
https://pubmed.ncbi.nlm.nih.gov/28730410
Autor:
Keiko Kita, Haruko Sakurama, Shigenobu Kishino, Jun Ogawa, Kousuke Mihara, Akinori Ando, Sakayu Shimizu, Satomi Takahashi
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 9, Pp 1855-1863 (2014)
The PUFAs include many bioactive lipids. The microbial metabolism of C18 PUFAs is known to produce their bioactive isomers, such as conjugated FAs and hydroxy FAs, but there is little information on that of C20 PUFAs. In this study, we aimed to obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de9558119b6b254705d6445b9d9f1bf
http://hdl.handle.net/2433/204519
http://hdl.handle.net/2433/204519
Publikováno v:
Journal of Bioscience and Bioengineering. 100:355-364
Conjugated fatty acids have attracted much attention as a novel type of biologically beneficial functional lipid. Some isomers of conjugated linoleic acid (CLA) reduce carcinogenesis, atherosclerosis, and body fat. Considering the use of CLA for medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056c38b68a53527a1d3d2842b1fc6908
https://doi.org/10.1263/jbb.100.355
https://doi.org/10.1263/jbb.100.355