Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kousik, Chandra"'
Autor:
Mawadda Alghrably, Giulia Bennici, Gabriela Szczupaj, Noura Alasmael, Somayah Qutub, Batoul Maatouk, Kousik Chandra, Michal Nowakowski, Abdul-Hamid Emwas, Mariusz Jaremko
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Human amylin (hIAPP) is found in the form of amyloid deposits within the pancreatic cells of nearly all patients diagnosed with type 2 diabetes mellitus (T2DM). However, rat amylin (rIAPP) and pramlintide - hIAPP analogs - are both non-toxic and non-
Externí odkaz:
https://doaj.org/article/614ee22388e14014915a674e337eeb56
Autor:
Shuruq Alsuhaymi, Upendra Singh, Inas Al-Younis, Najeh M. Kharbatia, Ali Haneef, Kousik Chandra, Manel Dhahri, Mohammed A. Assiri, Abdul-Hamid Emwas, Mariusz Jaremko
Publikováno v:
Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Since ancient times, the inhabitants of dry areas have depended on the date palm (Phoenix dactylifera L.) as a staple food and means of economic security. For example, dates have been a staple diet for the inhabitants of the Arabian Peninsul
Externí odkaz:
https://doaj.org/article/c6256b80a5a74b8291c857161f268c66
Autor:
Varsha P. Brahmkhatri, Amrinder Singh, Arpan Chakraborty, R Shankararama Sharma, Kousik Chandra, Hanudatta S. Atreya
Publikováno v:
Applied Surface Science Advances, Vol 11, Iss , Pp 100272- (2022)
The nanoparticle surfaces interact readily with biomolecules, including proteins forming a corona. The protein layer that directly interacts with the nanoparticle surface is usually explored. Non-covalent interactions of proteins in the second layer
Externí odkaz:
https://doaj.org/article/65674538e4b34d6aa17a586026e7b85a
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Human serum albumin (HSA) is the main zinc(II) carrier in blood plasma. The HSA site with the strongest affinity for zinc(II), multi-metal binding site A, is disrupted by the presence of fatty acids (FAs). Therefore, the FA concentration in the blood
Externí odkaz:
https://doaj.org/article/cb3e68d6422f48ffb62e68ce011f420e
Autor:
Joanna I. Lachowicz, Giusi Pichiri, Marco Piludu, Sara Fais, Germano Orrù, Terenzio Congiu, Monica Piras, Gavino Faa, Daniela Fanni, Gabriele Dalla Torre, Xabier Lopez, Kousik Chandra, Kacper Szczepski, Lukasz Jaremko, Mitra Ghosh, Abdul-Hamid Emwas, Massimo Castagnola, Mariusz Jaremko, Ewald Hannappel, Pierpaolo Coni
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 551 (2022)
Thymosin β4 (Tβ4) was extracted forty years agofrom calf thymus. Since then, it has been identified as a G-actin binding protein involved in blood clotting, tissue regeneration, angiogenesis, and anti-inflammatory processes. Tβ4 has also been impl
Externí odkaz:
https://doaj.org/article/d878e7bf64fa4f7fb226305eb1082f58
Publikováno v:
ACS Omega, Vol 2, Iss 8, Pp 4316-4327 (2017)
Externí odkaz:
https://doaj.org/article/1e4b8a410e84447fb8c3e1c48da55b89
Autor:
Abdul-Hamid Emwas, Kacper Szczepski, Benjamin Gabriel Poulson, Kousik Chandra, Ryan T. McKay, Manel Dhahri, Fatimah Alahmari, Lukasz Jaremko, Joanna Izabela Lachowicz, Mariusz Jaremko
Publikováno v:
Molecules, Vol 25, Iss 20, p 4597 (2020)
Studying disease models at the molecular level is vital for drug development in order to improve treatment and prevent a wide range of human pathologies. Microbial infections are still a major challenge because pathogens rapidly and continually evolv
Externí odkaz:
https://doaj.org/article/618e9b48a5a6471fb35ad8228888cdad
Autor:
Kousik Chandra, Abdul Hamid Emwas, Samah Al-Harthi, Zeyad Al-Talla, Dina Hajjar, Arwa Abdulaziz Makki, Ghada Khouqeer, Mariusz Jaremko
Publikováno v:
NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces ISBN: 9781839162091
Structural biology has come a long way since the first inception of multidimensional NMR. The dipole–dipole interaction between two spatially closed spins provides a powerful tool to probe macromolecules’ three-dimensional (3D) structure, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed7b5f72fb942aeb5e65c7249790f034
https://doi.org/10.1039/9781839165702-00001
https://doi.org/10.1039/9781839165702-00001
Autor:
Abdul-Hamid M. Emwas, Łukasz Jaremko, Mariusz Jaremko, Fatimah Almulhim, Samah Al-Harthi, Kousik Chandra
Publikováno v:
Molecular Omics. 17:719-724
Here, we implemented and validated a suite of selective and non-selective CPMG-filtered 1D and 2D TOCSY/HSQC experiments for metabolomics research. They facilitated the unambiguous identification of metabolites embedded in broad lipid and protein sig
Autor:
Hanudatta S. Atreya, Samah Al-Harthi, Łukasz Jaremko, Kousik Chandra, Fatimah Almulhim, Sujeesh Sukumaran, Mariusz Jaremko, Abdul-Hamid M. Emwas
Publikováno v:
RSC Advances. 11:8694-8700
NMR-based metabolomics, which emerged along with mass spectrometry techniques, is the preferred method for studying metabolites in medical research and food industries. However, NMR techniques suffer from inherently low sensitivity, regardless of the