Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Koushik Muralidharan"'
Autor:
Phoebe Valdes, Kenneth W. Henry, Michael Q. Fitzgerald, Koushik Muralidharan, Andrew B. Caldwell, Srinivasan Ramachandran, Lawrence S. B. Goldstein, William C. Mobley, Douglas R. Galasko, Shankar Subramaniam
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Non-familial Alzheimer’s disease (AD) occurring before 65 years of age is commonly referred to as early-onset Alzheimer’s disease (EOAD) and constitutes ~ 5–6% of all AD cases (Mendez et al. in Continuum 25:34–51, 2019). While EOAD e
Externí odkaz:
https://doaj.org/article/3ea7c071f924471b9c2a68f75dab7070
Autor:
Anudeep Yekula, Valentina R. Minciacchi, Matteo Morello, Huilin Shao, Yongil Park, Xuan Zhang, Koushik Muralidharan, Michael R. Freeman, Ralph Weissleder, Hakho Lee, Bob Carter, Xandra O. Breakefield, Dolores Di Vizio, Leonora Balaj
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Tumour cells release diverse populations of extracellular vesicles (EVs) ranging in size, molecular cargo, and function. We sought to characterize mRNA and protein content of EV subpopulations released by human glioblastoma (GBM) cells expressing a m
Externí odkaz:
https://doaj.org/article/8cd2c4798cf54a19a0cbbe15d8d6a0ba
Autor:
Anuroop Yekula, Anudeep Yekula, Koushik Muralidharan, Keiko Kang, Bob S. Carter, Leonora Balaj
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic tumor microenvironment (TME) plays a crucial role in the sustained growth, proliferation, and invasion of GBM. Several means of intercellular communication have been
Externí odkaz:
https://doaj.org/article/25a3cfc76007438bb38a28c7b8a49a5d
Autor:
Keiko M. Kang, Koushik Muralidharan, Anudeep Yekula, Julia L. Small, Zachary S. Rosh, Pamela S. Jones, Bob S. Carter, Leonora Balaj
Publikováno v:
Cancers, Vol 13, Iss 6, p 1227 (2021)
Liquid biopsy provides a minimally invasive platform for the detection of tumor-derived information, including hotspot mutations, such as BRAF V600E. In this study, we provide evidence of the technical development of a ddPCR assay for the detection o
Externí odkaz:
https://doaj.org/article/cdb708cdd7f74b97839fbc17cf68843e
Autor:
Lan Wang, Anudeep Yekula, Koushik Muralidharan, Julia L. Small, Zachary S. Rosh, Keiko M. Kang, Bob S. Carter, Leonora Balaj
Publikováno v:
Cancers, Vol 12, Iss 5, p 1219 (2020)
Sequencing studies have provided novel insights into the heterogeneous molecular landscape of glioblastoma (GBM), unveiling a subset of patients with gene fusions. Tissue biopsy is highly invasive, limited by sampling frequency and incompletely repre
Externí odkaz:
https://doaj.org/article/760ce3c604ff427095c6ac8232b5f739
Autor:
Syeda Maheen Batool, Koushik Muralidharan, Tiffany Hsia, Sarah Falotico, Austin S. Gamblin, Yulia B. Rosenfeld, Sirena K. Khanna, Leonora Balaj, Bob S. Carter
Publikováno v:
Clin Cancer Res
Purpose: Liquid biopsy offers an attractive platform for noninvasive tumor diagnosis, prognostication, and prediction of glioblastoma clinical outcomes. Prior studies report that 30% to 50% of GBM lesions characterized by EGFR amplification also harb
Autor:
Bob S. Carter, Leonora Balaj, Sirena K. Khanna, Yulia B. Rosenfeld, Austin S. Gamblin, Sarah Falotico, Tiffany Hsia, Koushik Muralidharan, Syeda Maheen Batool
Supplementary Table from Highly Sensitive EGFRvIII Detection in Circulating Extracellular Vesicle RNA of Glioma Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0599dd6c34399cfd8dfcf7f4cab8a573
https://doi.org/10.1158/1078-0432.22486211
https://doi.org/10.1158/1078-0432.22486211
Autor:
Bob S. Carter, Leonora Balaj, Sirena K. Khanna, Yulia B. Rosenfeld, Austin S. Gamblin, Sarah Falotico, Tiffany Hsia, Koushik Muralidharan, Syeda Maheen Batool
Purpose:Liquid biopsy offers an attractive platform for noninvasive tumor diagnosis, prognostication, and prediction of glioblastoma clinical outcomes. Prior studies report that 30% to 50% of GBM lesions characterized by EGFR amplification also harbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091a0108a0f1771984c30304442118c1
https://doi.org/10.1158/1078-0432.c.6532274.v1
https://doi.org/10.1158/1078-0432.c.6532274.v1
Autor:
Bob S. Carter, Leonora Balaj, Daniel P. Cahill, Pamela S. Jones, William T. Curry, Brian V. Nahed, Ganesh M. Shankar, Steven N. Kalkanis, Michael R. Chicoine, Chetan Bettegowda, Hakho Lee, Hui Zhang, Spencer Lau, Lan Wang, Keiko M. Kang, Zachary S. Rosh, Julia L. Small, Anudeep Yekula, Koushik Muralidharan
Purpose:Liquid biopsy offers a minimally invasive tool to diagnose and monitor the heterogeneous molecular landscape of tumors over time and therapy. Detection of TERT promoter mutations (C228T, C250T) in cfDNA has been successful for some systemic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41edfbda9606570750ed170ac6cb1fca
https://doi.org/10.1158/1078-0432.c.6530045.v1
https://doi.org/10.1158/1078-0432.c.6530045.v1
Autor:
Bob S. Carter, Leonora Balaj, Daniel P. Cahill, Pamela S. Jones, William T. Curry, Brian V. Nahed, Ganesh M. Shankar, Steven N. Kalkanis, Michael R. Chicoine, Chetan Bettegowda, Hakho Lee, Hui Zhang, Spencer Lau, Lan Wang, Keiko M. Kang, Zachary S. Rosh, Julia L. Small, Anudeep Yekula, Koushik Muralidharan
Supplementary File Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930d55a0f02de3ed0fe56d19d7d4cbd8
https://doi.org/10.1158/1078-0432.22478774
https://doi.org/10.1158/1078-0432.22478774