Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Koushik, Sowrirajan"'
Autor:
Sameer, Talwar, Pallavi, Pawar, Huiquan, Wu, Koushik, Sowrirajan, Suyang, Wu, Benoît, Igne, Richard, Friedman, Fernando J, Muzzio, James K, Drennen
Publikováno v:
The AAPS Journal. 24
An online near-infrared (NIR) spectroscopy platform system for real-time powder blending monitoring and blend endpoint determination was tested for a phenytoin sodium formulation. The study utilized robust experimental design and multiple sensors to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa8c6013525a0fb72478d4d072cf8f
https://doi.org/10.1208/s12248-022-00748-4
https://doi.org/10.1208/s12248-022-00748-4
Autor:
Huiquan Wu, Fernando J. Muzzio, Rick Friedman, German Drazer, James K. Drennen, Dheerja Reddy, Chandra Kanth Bandi, Pallavi Pawar, Sameer Talwar, Koushik Sowrirajan
Publikováno v:
Journal of pharmaceutical sciences. 108(1)
Accurate assessment of tablet content uniformity is critical for narrow therapeutic index drugs such as phenytoin sodium. This work presents a near-infrared (NIR)-based analytical method for rapid prediction of content uniformity based on a large num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4ce3b62b8b920c27b6580458155e94
https://pubmed.ncbi.nlm.nih.gov/30009795
https://pubmed.ncbi.nlm.nih.gov/30009795
Autor:
Mansoor A. Khan, Rohit Ramachandran, Viola Tokárová, František Štěpánek, Ondřej Kašpar, Koushik Sowrirajan, Sarang Oka, Huiquan Wu, Fernando J. Muzzio
Publikováno v:
Advanced Powder Technology. 26:315-322
The objective of the current work was to investigate the effect of liquid to solid ratio (L/S), impeller speed and the wet massing time on the critical quality attributes of granules in a high shear wet granulation process for a two component (API an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e55f3e1ecf3e86bd24019037c7fa6302
https://doi.org/10.1016/j.apt.2014.10.012
https://doi.org/10.1016/j.apt.2014.10.012
Publikováno v:
Society of Engineering Science 51st Annual Technical Meeting
The blending performance in a resonant acoustic mixer (RAM) was characterized. The system showed to be highly effective in blending low concentrations of cohesive active pharmaceutical ingredients (APIs) and lubricants. A summary of these results wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36efd74f307722100de373dc320b0e66
http://docs.lib.purdue.edu/ses2014/mss/pharmsolids/5
http://docs.lib.purdue.edu/ses2014/mss/pharmsolids/5
Autor:
Koushik Sowrirajan, Sarang Oka, Viola Tokárová, Ondřej Kašpar, Rohit Ramachandran, František Štěpánek
Publikováno v:
International journal of pharmaceutics. 458(2)
The X-ray micro-tomography (micro-CT) technique has been used to visualize the microstructure of granules produced by high shear wet granulation and the dynamic evolution of porosity during granule dissolution. Using acetaminophen (paracetamol) as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42400bd192f4497e1651d0264a80919
https://pubmed.ncbi.nlm.nih.gov/24409518
https://pubmed.ncbi.nlm.nih.gov/24409518