Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Koushi, Hidaka"'
Autor:
Akira Onodera, Takuya Shimomura, Hirohisa Ochi, Ryuto Sunada, Eiko Fukutomi, Koushi Hidaka, Yuichi Kawai
Publikováno v:
Journal of Xenobiotics, Vol 13, Iss 4, Pp 653-661 (2023)
Many people are exposed every day to vehicle exhaust particulates (VEPs), which are thought to be taken up by epithelial cells that are the first barrier in our biological defense. The study aim was to investigate how VEPs are processed in the lysoso
Externí odkaz:
https://doaj.org/article/de948f71ba6648e3b0bdfc5b826aa5db
Autor:
Ruby H.P. Law, Guojie Wu, Eleanor W.W. Leung, Koushi Hidaka, Adam J. Quek, Tom T. Caradoc-Davies, Devadharshini Jeevarajah, Paul J. Conroy, Nigel M. Kirby, Raymond S. Norton, Yuko Tsuda, James C. Whisstock
Publikováno v:
Blood Advances, Vol 1, Iss 12, Pp 766-771 (2017)
Abstract: The zymogen protease plasminogen and its active form plasmin perform key roles in blood clot dissolution, tissue remodeling, cell migration, and bacterial pathogenesis. Dysregulation of the plasminogen/plasmin system results in life-threate
Externí odkaz:
https://doaj.org/article/b3a0c868cfc44aa795c55be0ba7c2b58
Autor:
Akihiro Nakamura, Nobuyuki Honma, Yuma Tanaka, Yoshiyuki Suzuki, Yosuke Shida, Yuko Tsuda, Koushi Hidaka, Wataru Ogasawara
Publikováno v:
Analytical Chemistry. 94(5):2416-2424
Droplet-based microfluidic systems are a powerful tool for biological assays with high throughput. Water-in-oil droplets (WODLs) are typically used in droplet-based microfluidic systems to culture microorganisms and perform enzyme assays. However, be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6af88db80f18da88dab9b8f4912fc3
https://hdl.handle.net/20.500.14094/0100482017
https://hdl.handle.net/20.500.14094/0100482017
Publikováno v:
Bioconjugate Chemistry. 30:1979-1985
Protease inhibitors are used as both research tools and therapeutics. Many of these inhibitors consist of substrate amino acid sequence-derived structure with a transition state mimic to interact with the active site of the protease, suppressing enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8114d2821319f059abe53f8bb15f8d10
https://doi.org/10.1021/acs.bioconjchem.9b00195
https://doi.org/10.1021/acs.bioconjchem.9b00195
Autor:
Takafumi Tasaki, Souichi Nukuzuma, Chiyoko Nukuzuma, Tsutomu Takegami, Koushi Hidaka, Masanori Kameoka, Shigeki Sugiura, Kazuo Nakamichi
Publikováno v:
Japanese journal of infectious diseases. 74(1)
JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunocompromised patients. Study of PML-type JCPyV in vitro has been limited due to difficulty in efficient pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ade785b29c19d5d6f827d5e80efe61
https://pubmed.ncbi.nlm.nih.gov/32741932
https://pubmed.ncbi.nlm.nih.gov/32741932
Autor:
Kazuo Nakamichi, Takafumi Tasaki, Tsutomu Takegami, Chiyoko Nukuzuma, Shigeki Sugiura, Koushi Hidaka, Masanori Kameoka, Souichi Nukuzuma
Publikováno v:
Microbiology and Immunology. 62:524-530
JC polyomavirus (JCPyV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunocompromised patients. Archetype JCPyV circulates in the human population. There have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d2899d1a51df564fd0ddf522f6a27b
https://doi.org/10.1111/1348-0421.12632
https://doi.org/10.1111/1348-0421.12632
Autor:
James C. Whisstock, Tom T. Caradoc-Davies, Yuko Tsuda, Koushi Hidaka, Raymond S. Norton, Paul J. Conroy, Eleanor W. W. Leung, Guojie Wu, Nigel Kirby, Adam J. Quek, Ruby H. P. Law, Devadharshini Jeevarajah
Publikováno v:
Blood Advances. 1:766-771
The zymogen protease plasminogen and its active form plasmin perform key roles in blood clot dissolution, tissue remodeling, cell migration, and bacterial pathogenesis. Dysregulation of the plasminogen/plasmin system results in life-threatening hemor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f5b271fadfcf104b82665ca06061c1
https://doi.org/10.1182/bloodadvances.2016004150
https://doi.org/10.1182/bloodadvances.2016004150
Publikováno v:
FEBS Open Bio
HIV disease became a manageable chronic disease since combination antiretroviral therapy (cART) was introduced as the standard treatment regimen. However, the emergence of drug‐resistant viruses is a major problem associated with cART. A phenotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7705dfc1eae57a952293ee48d58309
http://www.lib.kobe-u.ac.jp/handle_kernel/90003907
http://www.lib.kobe-u.ac.jp/handle_kernel/90003907
Autor:
Masanori Kameoka, Ryota Kuroki, Dale J. Kempf, Motoyasu Adachi, Rajesh Sankaranarayanan, Jun Wang, Tooru Kimura, Koushi Hidaka, Jeffrey-Tri Nguyen, Yoshiaki Kiso, Yoshio Hayashi, Keith F. McDaniel
Publikováno v:
Journal of medicinal chemistry. 61(12)
The emergence of drug-resistant HIV from a widespread antiviral chemotherapy targeting HIV protease in the past decades is unavoidable and provides a challenge to develop alternative inhibitors. We synthesized a series of allophenylnorstatine-based p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9f002ba8584098db6a6bd02c70403f
https://pubmed.ncbi.nlm.nih.gov/29852069
https://pubmed.ncbi.nlm.nih.gov/29852069
Autor:
Souichi, Nukuzuma, Chiyoko, Nukuzuma, Masanori, Kameoka, Shigeki, Sugiura, Kazuo, Nakamichi, Takafumi, Tasaki, Koushi, Hidaka, Tsutomu, Takegami
Publikováno v:
Microbiology and immunology. 62(8)
JC polyomavirus (JCPyV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunocompromised patients. Archetype JCPyV circulates in the human population. There have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1d7b57ec06ceda9a419004400d1871e
https://pubmed.ncbi.nlm.nih.gov/29932215
https://pubmed.ncbi.nlm.nih.gov/29932215