Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Koushambi Mitra"'
Autor:
Nicolas A. Abrigo, Kara K. Dods, Chelsea A. Makovsky, Sandeep Lohan, Koushambi Mitra, Kaylee M. Newcomb, Anthony Le, Matthew C. T. Hartman
Publikováno v:
ACS Chemical Biology. 18:746-755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae50afccc9dc8344ec5dd139b0d64e5a
https://doi.org/10.1021/acschembio.2c00680
https://doi.org/10.1021/acschembio.2c00680
Publikováno v:
Chemical Communications. 55:5607-5610
Highly cytotoxic agents have found an important niche in targeted anticancer therapy. Here we develop a new light release strategy for the targeting of one of these agents, 2-pyrrolinodoxorubicin, showing dramatic enhancements in toxicity with light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8292dd157b95724fe3659b8318c05218
https://doi.org/10.1039/c9cc02050k
https://doi.org/10.1039/c9cc02050k
Autor:
Koushambi Mitra, Matthew C. T. Hartman
Publikováno v:
Organicbiomolecular chemistry. 19(6)
The intense far-red absorption and emission features have made silicon phthalocyanines (SiPcs) distinct from the structurally related porphyrin analogues. Unlike most other phthalocyanines, SiPcs possess two additional axial bonds which reduce aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b06736ac10a9649b480cfe6b668592a
https://pubmed.ncbi.nlm.nih.gov/33475120
https://pubmed.ncbi.nlm.nih.gov/33475120
Autor:
Jasmine N. Tutol, Sheena D'Arcy, Kierstin M Page, Regina A. Baglia, Steven O. Nielsen, Sheel C. Dodani, Jyothi Kallu, Koushambi Mitra, Sriharika Gottipolu, Kira R Mills, Darby Ball
Publikováno v:
Rsc Chemical Biology
Human phenol sulfotransferases mediate the transfer of a sulfuryl moiety from the activated sulfate donor PAPS to hydroxy-containing substrates, altering substrate solubility and charge to affect phase II metabolism and cell signaling. Here, we prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd675c07fbaadcd5e7a29045027f3e2
https://doi.org/10.26434/chemrxiv.13215167.v1
https://doi.org/10.26434/chemrxiv.13215167.v1
Autor:
Kara K. Dods, Matthew C. T. Hartman, Koushambi Mitra, Kaylee M Newcomb, Nicolas A Abrigo, Anthony Le
The discovery of high-affinity peptides to many intracellular targets has become feasible through the development of diverse macrocyclic peptide libraries. But lack of cell permeability is a key feature hampering the use of these peptides as therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1984ce4c68b1c0ed938befc99fcb010
https://doi.org/10.26434/chemrxiv.12445226.v1
https://doi.org/10.26434/chemrxiv.12445226.v1
The discovery of high-affinity peptides to many intracellular targets has become feasible through the development of diverse macrocyclic peptide libraries. But lack of cell permeability is a key feature hampering the use of these peptides as therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad090e547e0b7cd0e6537bbdf4ce531
https://doi.org/10.26434/chemrxiv.12445226
https://doi.org/10.26434/chemrxiv.12445226
Publikováno v:
RSC Med Chem
Cancer remains one of the leading causes of death worldwide. Conventional treatment of the disease is comprised of chemotherapy, radiation and surgery among other treatment approaches. Chemotherapy is plagued by multiple side-effects caused due to no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a65cc1fb9d61d9553f08dd5a79aa702
https://pubmed.ncbi.nlm.nih.gov/33479692
https://pubmed.ncbi.nlm.nih.gov/33479692
Publikováno v:
Angewandte Chemie. 130:10420-10424
Controlled generation of cytotoxic agents with near-IR light is a current focus of photoactivated cancer therapy, including that involving cytotoxic platinum species. Herein, we present a novel heptamethine cyanine scaffolded Pt(II) complex, IR797-Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2640e1bcda7d37cc403de7fb09ec17ca
https://doi.org/10.1002/ange.201806911
https://doi.org/10.1002/ange.201806911
Autor:
Shamik Majumdar, Dipankar Nandi, Koushambi Mitra, Akhil R. Chakravarty, Santosh Podder, Nandini Mukherjee
Publikováno v:
Dalton Transactions. 47:823-835
Copper(II) complexes [Cu(L1/L2/L3)(A)] (1–3), where H2A·HCl is a vitamin B6 Schiff base, viz. 3-hydroxy-5-(hydroxymethyl)-4-(((2-hydroxyphenyl)imino)methyl)-2-methylpyridin-1-ium chloride, L1 and L2 are 2-(2-pyridyl)benzimidazole based borondipyrr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0b2cf98d515bb057d4c5cef3c43c1e
https://doi.org/10.1039/c7dt03976j
https://doi.org/10.1039/c7dt03976j
Publikováno v:
Journal of Materials Chemistry B. 6:7373-7377
Herein, we report novel hyaluronic acid formulated nanoparticles containing a platinum(II) conjugated silicon(IV) phthalocyanine (SiPc-Pt-HA) for tumor targeted red light photodynamic therapy and chemotherapy. The SiPc-Pt-HA conjugate showed specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfbbfe6a67f462947e38fe0647a11a2
https://doi.org/10.1039/c8tb02533a
https://doi.org/10.1039/c8tb02533a