Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kourtney P Nickerson"'
Autor:
Maureen M Leonard, Yu Bai, Gloria Serena, Kourtney P Nickerson, Stephanie Camhi, Craig Sturgeon, Shu Yan, Maria R Fiorentino, Aubrey Katz, Barbara Nath, James Richter, Matthew Sleeman, Cagan Gurer, Alessio Fasano
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215132 (2019)
Background & aimsThe early steps in the pathophysiology of celiac disease (CD) leading to loss of tolerance to gluten are poorly described. Our aim was to use RNA sequencing of duodenal biopsies in patients with active CD, CD in remission, and non-CD
Externí odkaz:
https://doaj.org/article/37cde0542e58457ba589f2fd6a83c19e
Autor:
Kourtney P Nickerson, Craig R Homer, Sean P Kessler, Laura J Dixon, Amrita Kabi, Ilyssa O Gordon, Erin E Johnson, Carol A de la Motte, Christine McDonald
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101789 (2014)
In the latter half of the 20th century, societal and technological changes led to a shift in the composition of the American diet to include a greater proportion of processed, pre-packaged foods high in fat and carbohydrates, and low in dietary fiber
Externí odkaz:
https://doaj.org/article/1514363f40094ba4a92c127cae1639d9
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52132 (2012)
Crohn's disease (CD) is associated with intestinal dysbiosis evidenced by an altered microbiome forming thick biofilms on the epithelium. Additionally, adherent-invasive E. coli (AIEC) strains are frequently isolated from ileal lesions of CD patients
Externí odkaz:
https://doaj.org/article/eb395fb867a8479f9e80ed288cfb7e9e
Autor:
Bobby J. Cherayil, Smriti Verma, Rachel A Prescott, Alessio Fasano, Christina S. Faherty, Laura A. MacKenzie Ingano, Emily Hill, Kourtney P. Nickerson, Stefania Senger
Publikováno v:
Gut Microbes
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi. We examin
Autor:
Laura A. MacKenzie Ingano, Alba Miranda-Ribera, Rosiane Lima, Meryl Perlman, Alejandro Llanos-Chea, Alessio Fasano, Gloria Serena, Christina S. Faherty, Marcelo B. Sztein, Stefania Senger, Kourtney P. Nickerson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
Microbiology Spectrum
Microbiology Spectrum
Gastrointestinal infections cause significant morbidity and mortality worldwide. The complexity of human biology and limited insights into host-specific infection mechanisms are key barriers to current therapeutic development. Here, we demonstrate th
Autor:
Stefania Senger, Laura A. MacKenzie Ingano, Kourtney P. Nickerson, Gloria Serena, Timothy K. Lu, Alejandro Llanos-Chea, Robert J. Citorik, Alessio Fasano, Christina S. Faherty
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 68:509-516
Objective Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance
Autor:
Daniel T. Leung, Regina C. LaRocque, Rachel L. Becker, Firdausi Qadri, Stephen B. Calderwood, Ashraful Islam Khan, Mohammad Kamruzzaman, Kourtney P. Nickerson, Kamrul Islam, Edward T. Ryan, Meagan Kelly, Rajib Biswas, Leslie M. Mayo-Smith, Jenny M. Tam, Motaher Hossain, Samantha R. Giffen, Fahima Chowdhury, Pavol Kováč, Robert C. Kauffman, Alaina S. Ritter, Aklima Akter, Matthew K. Waldor, Richelle C. Charles, Jason B. Harris, Jens Wrammert, Peng Xu, Christina S. Faherty, Ana A. Weil, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Jatin M. Vyas
Publikováno v:
mBio
mBio, Vol 11, Iss 6 (2020)
mBio, Vol 11, Iss 6 (2020)
Cholera is a severe dehydrating illness of humans caused by Vibrio cholerae. V. cholerae is a highly motile bacterium that has a single flagellum covered in lipopolysaccharide (LPS) displaying O-specific polysaccharide (OSP), and V. cholerae motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743c07becbf36f8442324981e5725e8a
https://doi.org/10.1101/2020.10.08.332551
https://doi.org/10.1101/2020.10.08.332551
Autor:
Lael M. Yonker, Christina S. Faherty, Bernard B. Lanter, Rhianna M. Hibbler, Snaha Krishna Dogiparthi, Eliana Drenkard, Bryan P. Hurley, Kevin S. Gipson, Kourtney P. Nickerson, Alejandro Llanos-Chea
Publikováno v:
Infect Immun
Throughout the course of infection, many pathogens encounter bactericidal conditions that threaten the viability of the bacteria and impede the establishment of infection. Bile is one of the most innately bactericidal compounds present in humans, fun
Autor:
Kourtney P. Nickerson, Marcelo B. Sztein, Deepak Kumar, Renata C. Lima, Claire M. Fraser, Y. Zhang, Stefania Senger, Maria Fiorentino, Laura A. MacKenzie Ingano, William A. Flavahan, Alessio Fasano, Christina S. Faherty, S. Patel
Publikováno v:
EBioMedicine
EBioMedicine, Vol 31, Iss, Pp 92-109 (2018)
EBioMedicine, Vol 31, Iss, Pp 92-109 (2018)
Commensal microorganisms influence a variety of host functions in the gut, including immune response, glucose homeostasis, metabolic pathways and oxidative stress, among others. This study describes how Salmonella Typhi, the pathogen responsible for
Autor:
Andrew Harding, Alexander Rodriguez-Palacios, Scott K. Durum, Mahmoud A. Ghannoum, Sanja Ilic, Minh Lam, Kourtney P. Nickerson, Theresa T. Pizarro, Mauricio Retuerto, Mairi H. McLean, Colleen M. Croniger, Catherine Himmelman, Paola Menghini, Fabio Cominelli, Christine McDonald
Publikováno v:
Inflammatory Bowel Diseases
Background Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn’s disease (CD). Herein, we experimentally quantified the impact of 6-week supplementation with a commercial sweetener (Splenda; ingredients