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New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.

Autor: Riganas S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli-Zografou, 15771 Athens, Greece., Papanastasiou I, Foscolos GB, Tsotinis A, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2012 Nov 26; Vol. 55 (22), pp. 10241-61. Date of Electronic Publication: 2012 Nov 09.

Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.

Autor: Riganas S; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimioupoli-Zografou, 157 71 Athens, Greece., Papanastasiou I, Foscolos GB, Tsotinis A, Bourguignon JJ, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Pondiki S, Vamvakides A

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2012 May 15; Vol. 20 (10), pp. 3323-31. Date of Electronic Publication: 2012 Mar 24.

Computational study of adamantanes using floating basis functions.

Autor: Sabzyan, Hassan, Saed, Behnaz

Publikováno v: Structural Chemistry; Aug2014, Vol. 25 Issue 4, p1207-1216, 10p

Sigma Proteins: Evolution of the Concept of Sigma Receptors

Autor: Felix J. Kim, Gavril W. Pasternak

Two sigma receptor subtypes have been proposed, sigma1 and 2. Much of our understanding of this system is based on biochemical and pharmacological characterization of the cloned sigma1 receptor subtype (Sigma1). It has become clear that sigma recepto