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Autor:
Yoshiki Higuchi, Masayuki Masu, Koumei Yano, Shin-ichi Terawaki, Kensuke Shiomi, Hirofumi Komori, Takuya Katsutani, Kazuko Keino-Masu, Naoki Shibata, Yasuhito Shomura
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:758-761
Coiled-coil DIX1 (Ccd1) is a positive regulator that activates the canonical Wnt signalling pathway by inhibiting the degradation of the key signal transducer β-catenin. The C-terminal DIX domain of Ccd1 plays an important role in the regulation o