Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kouko Tatsumi"'
Autor:
Keita Ueda, Takao Imai, Taeko Ito, Tadao Okayasu, Shotaro Harada, Takefumi Kamakura, Kazuya Ono, Tatsuya Katsuno, Tatsuhide Tanaka, Kouko Tatsumi, Hiroshi Hibino, Akio Wanaka, Tadashi Kitahara
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundIncreased fall risk caused by vestibular system impairment is a significant problem associated with aging. A vestibule is composed of linear acceleration-sensing otoliths and rotation-sensing semicircular canals. Otoliths, composed of utric
Externí odkaz:
https://doaj.org/article/790ad3f08c124c15b11e6d2784d286bd
Autor:
Kouko Tatsumi, Kaoru Kinugawa, Ayami Isonishi, Masahiro Kitabatake, Hiroaki Okuda, Shoko Takemura, Tatsuhide Tanaka, Eiichiro Mori, Akio Wanaka
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain. Here, to
Externí odkaz:
https://doaj.org/article/4b3a053f7aa449d599730651a3f9bab9
Autor:
Shoko Morita-Takemura, Kazuki Nakahara, Sanae Hasegawa-Ishii, Ayami Isonishi, Kouko Tatsumi, Hiroaki Okuda, Tatsuhide Tanaka, Masahiro Kitabatake, Toshihiro Ito, Akio Wanaka
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Circulating endotoxins including lipopolysaccharides (LPS) cause brain responses such as fever and decrease of food and water intake, while pre-injection of endotoxins attenuates these responses. This phenomenon is called endotoxi
Externí odkaz:
https://doaj.org/article/0c82219c2dd74a5f92c57881f4da1d99
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247840 (2021)
Innate immunity is the first line of defense against bacterial infection and is initiated by macrophages. Sorting nexin 25 (SNX25) is an SNX family member and is reported to negatively regulate TGF-β signaling by enhancing TGF receptor degradation.
Externí odkaz:
https://doaj.org/article/1fdecda34cc445bd96553904d21a47ca
Autor:
Kouko Tatsumi, Ayami Isonishi, Miwako Yamasaki, Yoshie Kawabe, Shoko Morita-Takemura, Kazuki Nakahara, Yuki Terada, Takeaki Shinjo, Hiroaki Okuda, Tatsuhide Tanaka, Akio Wanaka
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
Astrocytes are the most abundant glia cell type in the central nervous system (CNS), and are known to constitute heterogeneous populations that differ in their morphology, gene expression and function. Although glial fibrillary acidic protein (GFAP)
Externí odkaz:
https://doaj.org/article/b29f0158ec2f4b529e7eb632337747ae
Autor:
Takeaki Shinjo, Tatsuhide Tanaka, Hiroaki Okuda, Akira T Kawaguchi, Kentaro Oh-Hashi, Yuki Terada, Ayami Isonishi, Shoko Morita-Takemura, Kouko Tatsumi, Masahiko Kawaguchi, Akio Wanaka
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196191 (2018)
Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiomyocyte death and precipitate life-threatening heart failure. Propofol has been proposed to protect cells or tissues against oxidative stress. However, the mec
Externí odkaz:
https://doaj.org/article/18d986fe79724274b85f706d839ef0ec
Autor:
Taeko Ito, Kouko Tatsumi, Yasumitsu Takimoto, Tadashi Nishimura, Takao Imai, Toshiaki Yamanaka, Noriaki Takeda, Akio Wanaka, Tadashi Kitahara
Publikováno v:
Brain Sciences, Vol 9, Iss 11, p 329 (2019)
When vestibular function is lost, vestibular compensation works for the reacquisition of body balance. For the study of vestibular dysfunction and vestibular compensation, surgical or chemical labyrinthectomy has been performed in various animal spec
Externí odkaz:
https://doaj.org/article/85749d64f65a410b831e4e81bb50b515
Autor:
Manabu Makinodan, Takahira Yamauchi, Kouko Tatsumi, Hiroaki Okuda, Yoshinobu Noriyama, Miyuki Sadamatsu, Toshifumi Kishimoto, Akio Wanaka
Publikováno v:
Journal of Central Nervous System Disease, Vol 2009, Iss 1, Pp 1-6 (2009)
Externí odkaz:
https://doaj.org/article/9b7f6a75a8ee4842870776e9d9873e5a
Autor:
Manabu Makinodan, Aya Okuda-Yamamoto, Daisuke Ikawa, Michihiro Toritsuka, Tomohiko Takeda, Sohei Kimoto, Kouko Tatsumi, Hiroaki Okuda, Yu Nakamura, Akio Wanaka, Toshifumi Kishimoto
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66124 (2013)
Demyelination is generally regarded as a consequence of oligodendrocytic cell death. Oligodendrocyte processes that form myelin sheaths may, however, degenerate and regenerate independently of the cell body, in which case cell death does not necessar
Externí odkaz:
https://doaj.org/article/04b2c59c936b4fd1b5c5595f30b349bf
Autor:
Tatsuhide Tanaka, Hiroaki Okuda, Ayami Isonishi, Yuki Terada, Masahiro Kitabatake, Takeaki Shinjo, Kazuya Nishimura, Shoko Takemura, Hidemasa Furue, Toshihiro Ito, Kouko Tatsumi, Akio Wanaka
Publikováno v:
Nature Immunology. 24:439-451
Cross-talk between peripheral neurons and immune cells is important in pain sensation. We identified Snx25 as a pain-modulating gene in a transgenic mouse line with reduced pain sensitivity. Conditional deletion of Snx25 in monocytes and macrophages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb51b5e32fa2cacbf6f6ad3b407b0061
https://doi.org/10.1038/s41590-022-01418-5
https://doi.org/10.1038/s41590-022-01418-5