Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Kouki Ohtsuka"'
Autor:
Shinichi Chisada, Kouki Ohtsuka, Masachika Fujiwara, Masao Yoshida, Satsuki Matsushima, Takashi Watanabe, Kanae Karita, Hiroaki Ohnishi
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
The MRE11A-RAD50-NBS1 complex activates the ataxia-telangiectasia mutated (ATM) pathway and plays a central role in genome homeostasis. The association of RAD50 mutations with disease remains unclear; hence, we adopted a medaka rad50 mutant to demons
Externí odkaz:
https://doaj.org/article/05f3553ffea54139b8c5214446831001
Autor:
Tsubasa Yoshida, Yohei Kojima, Ryusuke Shimada, Hidesato Tanabe, Koichi Tabei, Osamu Yanagida, Takashi Nikaido, Kouki Ohtsuka, Hiroaki Ohnishi, Nobutsugu Abe, Tadakazu Hisamatsu, Shinichi Takahashi
Publikováno v:
Case Reports in Gastroenterology, Vol 15, Iss 1, Pp 62-69 (2021)
Duodenal tumors with a sporadic adenoma-carcinoma sequence are extremely rare. For such clinically suspected cases without a specific family history, performing a comprehensive gene search is important to understand the germline mutation background.
Externí odkaz:
https://doaj.org/article/c6f6e0cc033941998432267b23f4ad81
Autor:
Yohei Kojima, Kouki Ohtsuka, Shun Ishii, Nobuyoshi Aso, Atsuko Ohki, Yoshikazu Hashimoto, Hirohisa Takeuchi, Hiroaki Ohnishi, Nobutsugu Abe
Publikováno v:
Case Reports in Gastroenterology, Vol 14, Iss 3, Pp 547-553 (2020)
Serine/threonine kinase 11 (STK11) is known as a critical tumor-suppressor gene that is frequently mutated in a broad spectrum of human cancers. Among these, the p.F354L mutation of STK11 has been identified in sporadic colon or lung cancer cases. He
Externí odkaz:
https://doaj.org/article/e7866d71e0ae4ff38241577dd2fd31d8
Autor:
Wataru Ogura, Kouki Ohtsuka, Sachiko Matsuura, Takahiro Okuyama, Satsuki Matsushima, Satoko Yamasaki, Hiroyuki Miyagi, Kumiko Sekiguchi, Hiroaki Ohnishi, Takashi Watanabe
Publikováno v:
Viruses, Vol 14, Iss 5, p 956 (2022)
In Japan, healthcare workers (HCWs) are vaccinated against measles, rubella, chickenpox, mumps, and hepatitis B to prevent nosocomial infection; however, some do not produce sufficient antibodies (“suboptimal responders”). This study compared imm
Externí odkaz:
https://doaj.org/article/d5d3fcabce4146d9972b5782d233034d
Autor:
Wataru Ogura, Kouki Ohtsuka, Masachika Fujiwara, Ryota Tanaka, Kumiko Sekiguchi, Hiroaki Ohnishi, Takashi Watanabe
Publikováno v:
Respiratory Medicine Case Reports, Vol 29, Iss , Pp - (2020)
Because epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are effective in the treatment of non-small cell lung cancer (NSCLC) patients with EGFR mutations, it is critical to obtain accurate EGFR mutation test results. For NSCLC
Externí odkaz:
https://doaj.org/article/75a1e2360ef74ce9bedd36343813ebfc
Autor:
Nobuyoshi Aso, Kouki Ohtsuka, Junji Shibahara, Hirotomo Koda, Teppei Morikawa, Nobutsugu Abe, Takashi Watanabe, Hiroaki Ohnishi
Publikováno v:
Surgery Today. 53:252-260
We examined the microsatellite instability of duodenal tumors to evaluate their molecular features associated with the adenoma-carcinoma sequence.Fifty-two non-ampullary duodenal epithelial tumors collected by endoscopic mucosal resection or surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398c2ac560f916c9ae3da6cc54bd3c28
https://doi.org/10.1007/s00595-022-02558-9
https://doi.org/10.1007/s00595-022-02558-9
Autor:
Ryota, Tanaka, Masachika, Fujiwara, Norihiko, Sakamoto, Hitomi, Suzuki, Keisei, Tachibana, Kouki, Ohtsuka, Koji, Kishimoto, Hiroshi, Kamma, Junji, Shibahara, Haruhiko, Kondo
Publikováno v:
Diagnostic Cytopathology. 50:394-403
The histological classifications of invasive lung adenocarcinoma subtypes are considered to predict patient prognosis after surgical treatment. The objectives of this study were to evaluate cytomorphological characteristics and proliferative activiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083bf0ebc3e8c906641a8210d111d9d0
https://doi.org/10.1002/dc.24978
https://doi.org/10.1002/dc.24978
Autor:
Shinichi Chisada, Kouki Ohtsuka, Masachika Fujiwara, Masao Yoshida, Satsuki Matsushima, Takashi Watanabe, Kanae Karita, Hiroaki Ohnishi
Mutations in the MRN-ATM pathway-related genes cause MRN-related diseases and ataxia-telangiectasia. However, the effect of RAD50 mutations on these diseases remains unclear. To understand the function of RAD50 in the pathogenesis of ataxia-telangiec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::319bf00bd5a23a7e825d4e94f8946ebf
https://doi.org/10.21203/rs.3.rs-2103020/v1
https://doi.org/10.21203/rs.3.rs-2103020/v1
Autor:
Kouki Ohtsuka, Hiroaki Ohnishi, Atsuko Ohki, Nobuyoshi Aso, Shun Ishii, Nobutsugu Abe, Yoshikazu Hashimoto, Hirohisa Takeuchi, Yohei Kojima
Publikováno v:
Case Reports in Gastroenterology. 14:547-553
Serine/threonine kinase 11 (STK11) is known as a critical tumor-suppressor gene that is frequently mutated in a broad spectrum of human cancers. Among these, the p.F354L mutation of STK11 has been identified in sporadic colon or lung cancer cases. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9c48c1c41f1b165a92959ba2cd0017f
https://doi.org/10.1159/000508929
https://doi.org/10.1159/000508929
Autor:
Hiroaki Ohnishi, Naoko Shimamori, Junji Shibahara, Naota Okabe, Satoko Yamasaki, Tomonori Kishino, Satsuki Matsushima, Kouki Ohtsuka, Takashi Watanabe, Takeshi Morii
Publikováno v:
Journal of Medical Ultrasonics. 47:617-623
Well-differentiated liposarcoma, the most common subtype of liposarcoma, should be discriminated from benign lipoma. However, features on sonography for discriminating these two types of tumor have not been fully investigated. The present study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de053a1c5055ca56b32c679a8ff6025b
https://doi.org/10.1007/s10396-020-01051-5
https://doi.org/10.1007/s10396-020-01051-5