Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kouki Nishikawa"'
Autor:
Shota Suzuki, Kotaro Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Atsunori Oshima, Yoshinori Fujiyoshi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Hydroxycarboxylic acid receptors (HCA) are expressed in various tissues and immune cells. HCA2 and its agonist are thus important targets for treating inflammatory and metabolic disorders. Only limited information is available, however, on t
Externí odkaz:
https://doaj.org/article/84bdb686a8d447adb1d134ac1866c6f1
Autor:
Shun Nakamura, Katsumasa Irie, Hiroo Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Yasunori Saitoh, Atsushi Tamura, Sachiko Tsukita, Yoshinori Fujiyoshi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The main components of tight junctions (TJ) are claudins that polymerize and form meshwork architectures called TJ strands. Here the authors present the 3.6 Å crystal structure of murine claudin-3 and show that residue P134 causes a bending of the t
Externí odkaz:
https://doaj.org/article/3282587ab8ef40f0a71dedabefc971b9
Autor:
Keiichi Izumikawa, Yuko Nobe, Harunori Yoshikawa, Hideaki Ishikawa, Yutaka Miura, Hiroshi Nakayama, Takashi Nonaka, Masato Hasegawa, Naohiro Egawa, Haruhisa Inoue, Kouki Nishikawa, Koji Yamano, Richard J. Simpson, Masato Taoka, Yoshio Yamauchi, Toshiaki Isobe, Nobuhiro Takahashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The 43-kDa trans-activating response region DNA-binding protein 43 (TDP-43) is a product of a causative gene for amyotrophic lateral sclerosis (ALS). Despite of accumulating evidence that mitochondrial dysfunction underlies the pathogenesis
Externí odkaz:
https://doaj.org/article/9971d9fd83d945bca18af986cb1ebe25
Autor:
Hironaka Tsukagoshi, Takamasa Suzuki, Kouki Nishikawa, Sakae Agarie, Sumie Ishiguro, Tetsuya Higashiyama
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118339 (2015)
Understanding the molecular mechanisms that convey salt tolerance in plants is a crucial issue for increasing crop yield. The ice plant (Mesembryanthemum crystallinum) is a halophyte that is capable of growing under high salt conditions. For example,
Externí odkaz:
https://doaj.org/article/aa67cd2893304b2f88aef8850bc766fe
Autor:
Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, Yutaka Kitano, Yoshinori Fujiyoshi
Publikováno v:
Journal of Molecular Biology. 435:168049
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64105fb3791c387d4d9977b893d4ffe
https://doi.org/10.1016/j.jmb.2023.168049
https://doi.org/10.1016/j.jmb.2023.168049
Autor:
Kazutoshi Tani, Tohru Terada, Kentaro Shimizu, Yoshinori Fujiyoshi, Yuichi Yokoyama, Akira Mizoguchi, Daisuke Kozai, Atsuhiro Shimada, Kouki Nishikawa
Publikováno v:
Biophys Rev
Recent advances in cryo-electron microscopy (cryo-EM) have enabled protein structure determination at atomic resolutions. Cryo-EM specimens are prepared by rapidly freezing a protein solution on a metal grid coated with a holey carbon film; this resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fd8335569145426f342998b42e6cb9
https://pubmed.ncbi.nlm.nih.gov/32162215
https://pubmed.ncbi.nlm.nih.gov/32162215
Autor:
Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, Yutaka Kitano, Yoshinori Fujiyoshi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:1-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117be42f7280fed0c88a82ee63dee95e
https://doi.org/10.1254/jpssuppl.96.0_1-b-p-009
https://doi.org/10.1254/jpssuppl.96.0_1-b-p-009
Autor:
Atsushi Tamura, Hiroshi Suzuki, Yoshinori Fujiyoshi, Shun Nakamura, Hiroo Tanaka, Kouki Nishikawa, Sachiko Tsukita, Katsumasa Irie, Yasunori Saitoh
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Tight junction is a cell adhesion apparatus functioning as barrier and/or channel in the paracellular spaces of epithelia. Claudin is the major component of tight junction and polymerizes to form tight junction strands with various morphologies that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe61784be3982ff9ae41ddb54570e60f
https://doi.org/10.1038/s41467-019-08760-7
https://doi.org/10.1038/s41467-019-08760-7
Autor:
Mizuki Takahashi, Kouki Nishikawa, Kousei Shimada, Akiko Kamegawa, Yoshinori Fujiyoshi, Nobutaka Numoto, Daisuke Kozai, Hiroyuki Hanzawa, Yutaka Kitano
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 94:2-Y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7a0342740da9ace7c1a4950e9a29d4e
https://doi.org/10.1254/jpssuppl.94.0_2-y-e1-1
https://doi.org/10.1254/jpssuppl.94.0_2-y-e1-1
Autor:
Yoshinori Fujiyoshi, Hiroshi Suzuki, Kouki Nishikawa, Kazutoshi Tani, Yuki Ogura, Katsumasa Irie, Sachiko Tsukita, Yasunori Saitoh, Atsushi Tamura
Publikováno v:
Science. 347:775-778
How a toxin makes epithelial sheets leaky The entire human body and its many compartments are shielded from their external environments by the barrier function of epithelial cell sheets. The paracellular barrier function of tight junctions (TJs) is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cea7c577f8ff3ba8acd5c110dbb1635
https://doi.org/10.1126/science.1261833
https://doi.org/10.1126/science.1261833