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pro vyhledávání: '"Kouji Kuzuya"'
Autor:
Tetsuo Yoshida, Minoru Yoshida, Makoto Hasegawa, Koshiki Mino, Ryuzo Sasaki, Koichi Koseki, Tamio Mizukami, Kouji Kuzuya, Ayu Inoue, Tatsuki Kunoh, Tatsuhiro Miura, Sueharu Horinouchi, Se Won Ki
Publikováno v:
ACS Chemical Biology. 6:229-233
GEX1A is a microbial product with antitumor activity. HeLa cells cultured with GEX1A accumulated p27(Kip) and its C-terminally truncated form p27*. GEX1A inhibited the pre-mRNA splicing of p27, producing p27* from the unspliced mRNA containing the fi