Výsledky vyhledávání - "Kouji Hatama"

Activation of Protein Kinase C Induces Internalization of the GABAC Receptors Expressed in Xenopus Oocytes

Autor: Kouji Hatama, Hajime Murakami, Yasuo Kizawa, Tadashi Kusama, Kiyoshige Saito

Publikováno v: The Japanese Journal of Physiology. 50:429-435

In a previous study, we showed that the protein kinase C (PKC) activator 4beta-phorbol 12-myristate 13-acetate (PMA) inhibited the gamma-aminobutyric acid (GABA)-gated currents in Xenopus oocytes expressing human rho1 GABA(C) receptors. To investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::593baa4c638e954ff982111d2fc0a3b9
https://doi.org/10.2170/jjphysiol.50.429

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Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation

Autor: Hajime Murakami, Yasuo Kizawa, George R. Uhl, Tadashi Kusama, Manabu Sakurai, Kouji Hatama

Publikováno v: Neuroscience letters. 255(1)

The mechanism of inhibition of human GABA C /GABA ρ receptors by protein kinase C (PKC) activation was investigated in Xenopus oocytes. Phorbol 12-myristate 13 acetate (PMA), a potent PKC activator, at 25 nM inhibited the currents through GABA ρ 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e91f4008d4ad1f3bfd9d9615deec5f
https://pubmed.ncbi.nlm.nih.gov/9839716

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