Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Kouji H. Harada"'
Autor:
Yukiko Fujii, Yoshihisa Kato, Masayuki Miyatake, Syunpei Akeda, Sigeru Nagata, Junpei Ando, Katsumi Kido, Chiho Ohta, Nobuyuki Koga, Kouji H. Harada, Koichi Haraguchi
Publikováno v:
Environment International, Vol 189, Iss , Pp 108685- (2024)
Exposure to per- and polyfluoroalkyl substances (PFAS) is of great concern for human health because of their persistence and potentially adverse effects. Dietary intake, particularly through aquatic products, is a significant route of human exposure
Externí odkaz:
https://doaj.org/article/a2559fe434814a819bcb0be76e0aaa23
Autor:
Atsuko Noguchi, Tohru Tezuka, Hiroko Okuda, Hatasu Kobayashi, Kouji H. Harada, Takeshi Yoshida, Shinji Akioka, Keiko Wada, Aya Takeya, Risako Kabata-Murasawa, Daiki Kondo, Ken Ishikawa, Takeshi Asano, Michimasa Fujiwara, Nozomi Hishikawa, Tomoyuki Mizukami, Toshiaki Hitomi, Shohab Youssefian, Yoshihiro Nagai, Manabu Tanaka, Kaoru Eto, Hideaki Shiraishi, Fumimasa Amaya, Akio Koizumi, Tsutomu Takahashi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6832 (2024)
Familial episodic pain syndrome (FEPS) is an early childhood onset disorder of severe episodic limb pain caused mainly by pathogenic variants of SCN11A, SCN10A, and SCN9A, which encode three voltage-gated sodium channels (VGSCs) expressed as key dete
Externí odkaz:
https://doaj.org/article/8ecf42c31d3f41a98eac36f023956cb5
Autor:
Kazuyoshi Furukawa, Kahori Okamoto-Matsuda, Kouji H. Harada, Mutsuko Minata, Toshiaki Hitomi, Hatasu Kobayashi, Akio Koizumi
Publikováno v:
Environmental Health and Preventive Medicine, Vol 29, Pp 21-21 (2024)
Background: Perfluorooctanoic acid (PFOA) is one of the major per- and polyfluoroalkyl substances. The role of ATP-binding cassette (ABC) transporters in PFOA toxicokinetics is unknown. Methods: In this study, two ABC transporters, ABCB1 and ABCB4, w
Externí odkaz:
https://doaj.org/article/6a296a2c154f4485b0607379ad84edc1
Autor:
Yohei Mineharu, Yasuhisa Nakamura, Noriaki Sato, Takahiko Kamata, Yuki Oichi, Tomoko Fujitani, Takeshi Funaki, Yasushi Okuno, Susumu Miyamoto, Akio Koizumi, Kouji H. Harada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Moyamoya disease (MMD) is a rare cerebrovascular disease endemic in East Asia. The p.R4810K mutation in RNF213 gene confers a risk of MMD, but other factors remain largely unknown. We tested the association of gut microbiota with MMD. Fecal
Externí odkaz:
https://doaj.org/article/64f5bbac517244d8ae716a8bd36e886e
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 63-63 (2023)
Background: Zinc absorption and competition among gut bacteria have been reported in animal studies. Thus, gut bacteria may modify zinc availability in humans. Metabolism of intestinal bacteria is known to be necessary for the activation of several p
Externí odkaz:
https://doaj.org/article/b793fef201684eebae54b967457f5d5e
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/ba9863ea57724deb97b03542e1e1c7b9
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 38-38 (2023)
Background: Per- and polyfluoroalkyl substances (PFASs) are highly fluorinated organic compounds that have been widely used in industry during the past few decades. The main exposure routes for PFASs are thought to be the diet, drinking water, and du
Externí odkaz:
https://doaj.org/article/616de4a56a46455991c573cef3b43479
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 27-27 (2023)
Background: In the Great East Japan Earthquake of 11 March 2011, an earthquake and accompanying tsunami struck the Tohoku region of northeastern Japan. Buildings collapsed and the tsunami spread waste, including hazardous materials. This study aimed
Externí odkaz:
https://doaj.org/article/244205610144424dbb5fe3a7218b4bd8
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Isoflavones found in soy products are a promising class of nutrients that may have a positive effect on human health. In particular, the phytoestrogen metabolite equol is associated with a reduced risk of developing female hormone-related di
Externí odkaz:
https://doaj.org/article/a4863bb84aea4f3d9b6f1ae2227c98d2
Autor:
Nozomu Ozaki, Hiroko Okuda, Hatasu Kobayashi, Kouji H. Harada, Sumiko Inoue, Shohab Youssefian, Akio Koizumi
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Brachydactyly type A1 (BDA1) is an autosomal dominant disorder characterized by uniform shortening of the middle phalanges in all digits. It is associated with variants in the Indian Hedgehog (IHH) gene, which plays a key role in
Externí odkaz:
https://doaj.org/article/ff359c3e9a0949ae8577323a034cb113