Zobrazeno 1 - 10
of 726
pro vyhledávání: '"Kouji Matsushima"'
Autor:
Yugo Okabe, Etsuko Toda, Hirokazu Urushiyama, Yuya Terashima, Shinobu Kunugi, Yusuke Kajimoto, Mika Terasaki, Kouji Matsushima, Akira Saito, Yasuhiro Yamauchi, Takahide Nagase, Akira Shimizu, Yasuhiro Terasaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The accumulation of monocyte-derived macrophages in the lung tissue during inflammation is important for the pathogenesis of fibrotic lung disease. Deficiencies in chemokine receptors CCR2 and CCR5 and their ligands, which mediate monocyte/m
Externí odkaz:
https://doaj.org/article/cfa154cc344f4a1a9d413d09cb985598
Autor:
Miho Kurokawa, Takeshi Goya, Motoyuki Kohjima, Masatake Tanaka, Sadahiro Iwabuchi, Shigeyuki Shichino, Satoshi Ueha, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro, Hideo Suzuki, Masaki Kato, Shinichi Hashimoto, Hideo Matsuda, Kouji Matsushima, Yoshihiro Ogawa
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Acute liver failure (ALF) is a life-threatening disorder that progresses from self-limiting acute liver injury (ALI). Microcirculatory disturbance characterized by sinusoidal hypercoagulation and subsequent massive hypoxic hepatoc
Externí odkaz:
https://doaj.org/article/f24b7de720914341bdd83383c484cd32
Autor:
Yuichi Tsuchiya, Takao Seki, Kenta Kobayashi, Sachiko Komazawa-Sakon, Shigeyuki Shichino, Takashi Nishina, Kyoko Fukuhara, Kenichi Ikejima, Hidenari Nagai, Yoshinori Igarashi, Satoshi Ueha, Akira Oikawa, Shinya Tsurusaki, Soh Yamazaki, Chiharu Nishiyama, Tetuo Mikami, Hideo Yagita, Ko Okumura, Taketomo Kido, Atsushi Miyajima, Kouji Matsushima, Mai Imasaka, Kimi Araki, Toru Imamura, Masaki Ohmuraya, Minoru Tanaka, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Liver fibrosis results from chronic liver injury triggered by factors such as viral infection, excess alcohol intake, and lipid accumulation. However, the mechanisms underlying liver fibrosis are not fully understood. Here, we demonstrate th
Externí odkaz:
https://doaj.org/article/634090b816f84d4c88ef880ddf06cc84
Autor:
Ying-Yi Li, Kazuyuki Kuroki, Tetsuro Shimakami, Kazuhisa Murai, Kazunori Kawaguchi, Takayoshi Shirasaki, Kouki Nio, Saiho Sugimoto, Tomoki Nishikawa, Hikari Okada, Noriaki Orita, Hideo Takayama, Ying Wang, Phuong Doan Thi Bich, Astuya Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Takeshi Shimaoka, Noriko Tabata, Miho Watanabe-Takahashi, Kiyotaka Nishikawa, Hiroshi Yanagawa, Motoharu Seiki, Kouji Matsushima, Taro Yamashita, Shuichi Kaneko, Masao Honda
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 533-558 (2023)
Background & Aims: Hepatitis B virus (HBV) infection is difficult to cure owing to the persistence of covalently closed circular viral DNA (cccDNA). We performed single-cell transcriptome analysis of newly established HBV-positive and HBV-negative he
Externí odkaz:
https://doaj.org/article/5994dbd6cb574256b719639b085d8fe8
Autor:
Worachat Namangkalakul, Shigenori Nagai, Chengxue Jin, Ken-ichi Nakahama, Yuki Yoshimoto, Satoshi Ueha, Kazunari Akiyoshi, Kouji Matsushima, Tomoki Nakashima, Masaki Takechi, Sachiko Iseki
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Fibroblast growth factor (FGF) signaling plays essential roles in various biological events. FGF18 is one of the ligands to be associated with osteogenesis, chondrogenesis and bone healing. The mouse critical-sized calvarial defect healing induced by
Externí odkaz:
https://doaj.org/article/81cdec4b4dc8450da5d5cbe4e3b6cf0d
Autor:
Abigail Ekuban, Shigeyuki Shichino, Cai Zong, Frederick Adams Ekuban, Kazuo Kinoshita, Sahoko Ichihara, Kouji Matsushima, Gaku Ichihara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract 1,2-Dichloropropane (1,2-DCP), a synthetic organic solvent, has been implicated in causality of cholangiocarcinoma (bile duct cancer). 1,2-DCP-induced occupational cholangiocarcinoma show a different carcinogenic process compared to common c
Externí odkaz:
https://doaj.org/article/3fe29182a55b4aa789484191d0ea4d8f
Autor:
Shigeyuki Shichino, Satoshi Ueha, Shinichi Hashimoto, Tatsuro Ogawa, Hiroyasu Aoki, Bin Wu, Chang-Yu Chen, Masahiro Kitabatake, Noriko Ouji-Sageshima, Noriyoshi Sawabata, Takeshi Kawaguchi, Toshitugu Okayama, Eiji Sugihara, Shigeto Hontsu, Toshihiro Ito, Yasunori Iwata, Takashi Wada, Kazuho Ikeo, Taka-Aki Sato, Kouji Matsushima
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Terminator-assisted solid-phase cDNA amplification and sequencing (TASseq) uses a terminator, terminal transferase and bead-based platform to improve generation of single-cell RNA-seq libraries.
Externí odkaz:
https://doaj.org/article/23b6ea550be047c69c0754a4e9cf239e
Autor:
Sadahiro Iwabuchi, Tomohide Tsukahara, Toshitugu Okayama, Masahiro Kitabatake, Hideki Motobayashi, Shigeyuki Shichino, Tadashi Imafuku, Kenzaburo Yamaji, Kyohei Miyamoto, Shinobu Tamura, Satoshi Ueha, Toshihiro Ito, Shin-ichi Murata, Toshikazu Kondo, Kazuho Ikeo, Yutaka Suzuki, Kouji Matsushima, Michinori Kohara, Toshihiko Torigoe, Hiroki Yamaue, Shinichi Hashimoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being developed world over. We investigated the possibility of producing artificial antibodies from the formalin fixation and paraffin-embedding (FFP
Externí odkaz:
https://doaj.org/article/32149fe894984f60b5857c5a88f4c29c
Autor:
Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The stromal fibroblast population in the colon is composed of heterogeneous and distinct cell subtypes that play a crucial role in the development of colitis and colon cancer. Here the authors generate IL-11 reporter mice and characterize the origin
Externí odkaz:
https://doaj.org/article/3db3ac661ebb40e88567f28d3824a2f8
Autor:
Akihiro Hosoi, Kazuyoshi Takeda, Koji Nagaoka, Tamaki Iino, Hirokazu Matsushita, Satoshi Ueha, Shin Aoki, Kouji Matsushima, Masato Kubo, Teppei Morikawa, Kazutaka Kitaura, Ryuji Suzuki, Kazuhiro Kakimi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a76c14697c4c468abac1a2cb93525325