ACE2 knockout hinders SARS-CoV-2 propagation in iPS cell-derived airway and alveolar epithelial cells

Autor: Ryo Niwa, Kouji Sakai, Mandy Siu Yu Lung, Tomoko Matsumoto, Ryuta Mikawa, Shotaro Maehana, Masato Suzuki, Yuki Yamamoto, Thomas L. Maurissen, Ai Hirabayashi, Takeshi Noda, Makoto Kubo, Shimpei Gotoh, Knut Woltjen

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, continues to spread around the world with serious cases and deaths. It has also been suggested that different genetic variants in the human genome affect b

Externí odkaz: https://doaj.org/article/848a17b47661450f8d9a4795aaba1afe

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

Autor: Xin Yin, Laura Riva, Yuan Pu, Laura Martin-Sancho, Jun Kanamune, Yuki Yamamoto, Kouji Sakai, Shimpei Gotoh, Lisa Miorin, Paul D. De Jesus, Chih-Cheng Yang, Kristina M. Herbert, Sunnie Yoh, Judd F. Hultquist, Adolfo García-Sastre, Sumit K. Chanda

Publikováno v: Cell Reports, Vol 34, Iss 2, Pp 108628- (2021)

Summary: Recent studies have profiled the innate immune signatures in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular responses to viral challenge may affect disease severity. Yet the mole

Externí odkaz: https://doaj.org/article/659782da5add4a8d89417e095929b9cb

Nationwide Molecular Epidemiology of Measles Virus in Japan Between 2008 and 2017

Autor: Fumio Seki, Masahiro Miyoshi, Tatsuya Ikeda, Haruna Nishijima, Miwako Saikusa, Masae Itamochi, Hiroko Minagawa, Takako Kurata, Rei Ootomo, Jumboku Kajiwara, Takashi Kato, Katsuhiro Komase, Keiko Tanaka-Taya, Tomimasa Sunagawa, Kazunori Oishi, Nobuhiko Okabe, Hirokazu Kimura, Shigeru Suga, Kunihisa Kozawa, Noriyuki Otsuki, Yoshio Mori, Komei Shirabe, Makoto Takeda, Measles Virus Surveillance Group of Japan, Technical Support Team for Measles Control in Japan, Rika Komagome, Asami Ohnishi, Hiroyuki Saito, Mie Sasaki, Kenichi Komabayashi, Atsuko Kanari, Tsutomu Tamura, Kazunari Yamamoto, Kanako Ishikawa, Fuminori Mizukoshi, Hiroyuki Tsukagoshi, Yasutaka Ogawa, Takashi Nakada, Ai Kasuga, Tomoko Ogawa, Hajime Yokoi, Rieko Suzuki, Hideaki Shimizu, Satoko Kanazawa, Masayuki Oonuma, Nagano Environ, Kanako Nishizawa, Yuichiro Okamura, Asaka Ikegaya, Takaharu Maehata, Toshihiko Furuta, Masaya Nakazawa, Yoshihiro Yasui, Shinichiro Shibata, Tsuyoshi Kuzuguchi, Yasunori Tanaka, Hajime Kusuhara, Kayo Aoki, Sachi Hirata, Akiko Nagasao, Daiki Kanbayashi, Atsushi Kaida, Tatsuya Miyoshi, Miki Ogi, Taku Uemura, Shinya Kawanishi, Masaki Hiragakiuchi, Machi Inada, Takashi Nishiyama, Chika Tatsumi, Masako Hamano, Naoki Shigemoto, Fujii Yoshiki, Sachiko Murata, Yukari Terajima, Yumiko Kawakami, Yuki Ashizuka, Chinami Wasano, Misato Tachibana, Akiko Honda, Takashi Sakai, Kaori Nishizawa, Yu Matsuura, Mutsuyo Gokuden, Minori Oyama, Kenji Someya, Yuichiro Nakatsu, Maino Tahara, Kouji Sakai, Yukari Yamada, Kumi Ueno-Yamamoto, Yuki Tada, Tomoe Shimada, Kazuyo Yamashita, Hitomi Kinoshita, Takuri Takahashi, Kazutoshi Nakashima, Hajime Kamiya, Kiyosu Taniguchi, Yoshinori Yasui

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

Genotyping evidence that supports the interruption of endemic measles virus (MV) transmission is one of the essential criteria to be verified in achieving measles elimination. In Japan since 2014, MV genotype analyses have been performed for most of

Externí odkaz: https://doaj.org/article/71b1dae1082c40a8b41b4f5870bb953c

Complete genome constellations of two bovine rotavirus A strains isolated in Japan reveal a unique T9 NSP3 genotype.

Autor: HASAN, Md Amirul, Masato SUZUKI, Kouji SAKAI, KABIR, Md Humayun, Yu MIYAOKA, Hakimullah HAKIM, Chisaki KADOTA, Dany SHOHAM, Kazuaki TAKEHARA

Publikováno v: Journal of Veterinary Medical Science; 2023, Vol. 85 Issue 9, p998-1003, 6p

Emergence of a novel mobile RND-type efflux pump gene cluster,tmexC3D2-toprJ1b, inPseudomonasspecies

Autor: Aki Hirabayashi, Kazunari Sei, Masato Suzuki, Kouji Sakai, Takashi Furukawa, Nagi Niida, Shotaro Maehana, Ryotaro Eda, Hidero Kitasato

Tigecycline exhibits promising activity against multidrug-resistant Gram-negative bacteria (MDR-GNB), whose infections are difficult to treat with antimicrobials. However, mobile tigecycline resistance genes, such astmexCD-toprJ, have emerged in Ente

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92e923db8686f31111637607c7f27292
https://doi.org/10.1101/2021.07.26.453812