Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kouichirou Wada"'
Autor:
Ka Bian, Yu Chen Lee, Emil Martin, Ferid Murad, Yoshinori Kamisaki, Fariba Behbod, Kouichirou Wada, Karen L. Davis, Barbaros Balabanli
Publikováno v:
Proceedings of the National Academy of Sciences. 95:11584-11589
Homogenates from rat spleen and lung could modify nitrotyrosine-containing BSA. With incubation, nitrotyrosine-containing BSA lost its epitope to a monoclonal antibody that selectively recognized nitrotyrosine-containing proteins. In the presence of
Autor:
Goshi Shiota, Yosuke Kishimoto, Hironaka Kawasaki, Kentaro Nakamoto, Kumiyo Ashida, Yoshinori Kamisaki, Kouichirou Wada, Tadao Itoh, Yasuaki Hirooka
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 123:489-495
Carcinogenesis is a multistep process. Most hepatocellular carcinoma (HCC) is preceded by liver cirrhosis, but the genetic changes involved in cirrhosis are not known well. The present study was conducted to evaluate aberration of the retinoblastoma
Autor:
Tadao Itoh, Yosuke Kishimoto, Yoshinori Kamisaki, Hironaka Kawasaki, Masayuki Kitano, Kouichirou Wada, Kentaro Nakamoto
Publikováno v:
Pharmacology. 55:154-164
We investigated the effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats. Under pentobarbital anesthesia, the celiac artery was clamped for 30 min and reperfused for 60 min. Cimetidine, famotidine and omeprazo
Publikováno v:
Pharmacology. 54:203-210
We examined the effect of acetaminophen, an analgesic and antipyretic drug, on acute gastric mucosal injury induced by ischemia-reperfusion in rats. Ischemia-reperfusion was induced by clamping the celiac artery for 30 min with a small clip. Sixty mi
Autor:
Kentaro Nakamoto, Hironaka Kawasaki, Kouichirou Wada, Kumiyo Ashida, Yosuke Kishimoto, Yoshinori Kamisaki, Tadao Itoh
Publikováno v:
Life Sciences. 60:PL127-PL133
The rat model of acute gastric damage induced by ischemia-reperfusion (I-R) has been used to evaluate the protective effect of various drugs on gastric injury. However, the quantitative expression state of cyclooxygenase-2 (COX-2), a protein which in
Autor:
Yosuke Kishimoto, Yoshinori Kamisaki, Masayuki Kitano, Kentaro Nakamoto, Tadao Itoh, Kouichirou Wada
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 685:343-347
A highly sensitive and simple isocratic high-performance liquid chromatographic method was developed for determination of 3-nitrotyrosine in human plasma with precolumn derivatization with 4-fluoro-7-nitrobenzo-2-oxa-1,3-diazole. The precision of the
Autor:
Goshi Shiota, Yoshinori Kamisaki, Masayuki Kitano, Tadao Itoh, Yosuke Kishimoto, Kouichirou Wada, Hironaka Kawasaki, Kentaro Nakamoto, Takeaki Suou
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 122:585-589
Most hepatocellular carcinoma (HCC) is preceded by liver cirrhosis, but the genetic changes involved in cirrhosis are not well understood. We therefore studied loss of heterozygosity (LOH) in cirrhotic and neoplastic foci in livers of 14 patients wit
Autor:
Minoru Nakano, Kouichirou Wada, Kazuo Umemura, Hiroshi Nishiyama, Yoshiharu Takiguchi, Abby R Saniabadi, Mitsuyoshi Nakashima
Publikováno v:
Atherosclerosis. 122:217-224
Reocclusion following thrombolysis is a major limitation of thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA) because denuded vessel wall exposed to blood following thrombolysis is a favourable surface for platelet and l
Publikováno v:
European Journal of Pharmacology. 296:335-340
We studied the direct effects of cystathionine on human leukocyte-generated or xanthine-xanthine oxidase-derived superoxide radicals in vitro. Washed leukocyte suspensions (10(6) cells/ml) prepared from healthy male volunteers were stimulated with ph
Publikováno v:
Amino Acids. 10:49-57
Superfusion of synaptosomes prepared from rat olfactory bulb revealed constant basal release of endogenous taurine (Tau), aspartate (Asp), glutamate (Glu) andγ-aminobutyrate (GABA): their release rates were 110.4 ± 13.0, 30.3 ± 6.7, 93.7 ± 13.1,