Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kouichi Sugaya"'
Autor:
Ryogo Ukai, Hideaki Uchida, Kouichi Sugaya, Jun-ichi Onose, Naomasa Oshiro, Takeshi Yasumoto, Naoki Abe
Publikováno v:
Toxins, Vol 16, Iss 2, p 89 (2024)
Ciguatoxins (CTXs) stand as the primary toxins causing ciguatera fish poisoning (CFP) and are essential compounds distinguished by their characteristic polycyclic ether structure. In a previous report, we identified the structures of product ions gen
Externí odkaz:
https://doaj.org/article/4e12075f56b7474b9516fcaf5e418b89
Autor:
Yasukiyo Yoshioka, Yue Qi Ye, Kiyoshi Okada, Kayoko Taniguchi, Ayaka Yoshida, Kouichi Sugaya, Jun-ichi Onose, Hiroyuki Koshino, Shunya Takahashi, Arata Yajima, Shunsuke Yajima, Naoki Abe
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80931 (2013)
Tumor necrosis factor alpha (TNF-α), a central mediator of the inflammatory response, is released from basophilic cells and other cells in response to a variety of proinflammatory stimuli. Vialinin A is a potent inhibitor of TNF-α production and is
Externí odkaz:
https://doaj.org/article/1f3bccd1e6ec4d919bf1fa264d0b0895
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 83:1181-1192
Interaction between foods and drugs is an important consideration in pharmaceutical therapy. Therefore, here, we examined the suppressive effects of the extracts from seven edible herbs on the induction of CYP3A4 gene expression in rifampicin-treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a564927d02228ed8bb8d0257efc5d81
https://doi.org/10.1080/09168451.2019.1608802
https://doi.org/10.1080/09168451.2019.1608802
Publikováno v:
Bioscience, biotechnology, and biochemistry. 83(7)
Interaction between foods and drugs is an important consideration in pharmaceutical therapy. Therefore, here, we examined the suppressive effects of the extracts from seven edible herbs on the induction of CYP3A4 gene expression in rifampicin-treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e09223e68659250644add640fec5ca6
https://pubmed.ncbi.nlm.nih.gov/31032736
https://pubmed.ncbi.nlm.nih.gov/31032736
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(6)
Bisorbicillinol, which is isolated from Trichoderma sp. USF2690, is an inhibitor of β-hexosaminidase release and tumor necrosis factor (TNF)-α, and Interleukin (IL)-4 secretion from rat basophilic leukemia (RBL-2H3) cells, with IC50 values of 2.8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216527031f0fa6db753fc0013d29dd32
https://pubmed.ncbi.nlm.nih.gov/30711393
https://pubmed.ncbi.nlm.nih.gov/30711393
Autor:
Jun-ichi Onose, Tatsuya Katho, Asako Hiroi, Naoki Abe, Rie Hatsumata, Nami Miyakawa, Zeineb Brahmi, Emi Yakou, Kouichi Sugaya
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 76:1028-1031
Two effective cytochrome P450 (CYP) inhibitors were isolated from tarragon, Artemisia dracunculus. Their structures were spectroscopically identified as 2E,4E-undeca-2,4-diene-8,10-diynoic acid isobutylamide (1) and 2E,4E-undeca-2,4-diene-8,10-diynoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe74bab97dce2fa9e166bcd7e6cef3c
https://doi.org/10.1271/bbb.120006
https://doi.org/10.1271/bbb.120006
Autor:
Naoki Abe, Jun-ichi Onose, Katsuaki Yasunaga, Hiroyuki Koshino, Yayoi Hongo, Kouichi Sugaya, Kunie Yoshikawa
Publikováno v:
Tetrahedron Letters. 49:654-657
Biosynthetic feeding studies of [1- 13 C], [2- 13 C], and [1,2- 13 C 2 ]-labeled sodium acetates into 5-epihydroxyvertinolide, a new sorbicillinoid, gives an incorporation pattern that proves the γ-lactone ring formation associated with a ring cleav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5720bf0f9be7dc531eec44115192d44
https://doi.org/10.1016/j.tetlet.2007.11.121
https://doi.org/10.1016/j.tetlet.2007.11.121
Autor:
Jun-ichi Onose, Zeineb Brahmi, Kouichi Sugaya, Mio Yamasato, Naoki Abe, Sakurako Shigeto, Yuna Kusakari, Hitomi Niwa
Publikováno v:
Bioscience, biotechnology, and biochemistry. 75(11)
A highly polymethylated flavone that effectively inhibited cytochrome P450s (CYPs) 1A2 and 3A4 (IC(50) = 2.41 and 1.71 µM) in vitro was isolated from thyme leaves (Thymus saturoides) purchased from a Japanese market. Its structure was spectroscopica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbff9081bea2170bd3a6edf52b4690b
https://pubmed.ncbi.nlm.nih.gov/22056445
https://pubmed.ncbi.nlm.nih.gov/22056445
Publikováno v:
International journal of molecular medicine. 27(1)
Antioxidative flavonoids are used to reduce the risk of cardiovascular diseases in humans. However, the precise mechanism for the anti-atherosclerotic actions of flavonoids remains to be elucidated. In the present study, to assess the mechanism for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048943e9402f11376f4a838a44822aa4
https://pubmed.ncbi.nlm.nih.gov/21069260
https://pubmed.ncbi.nlm.nih.gov/21069260
Autor:
Shunya Takahashi, Yue Qi Ye, Kouichi Sugaya, Kunie Yoshikawa, Katsuaki Yasunaga, Hiroyuki Koshino, Chun Xie, Naoki Abe, Jun-ichi Onose
Publikováno v:
Biologicalpharmaceutical bulletin. 31(5)
Thelephora vialis is a mushroom that grows in symbiosis with pine trees in Yunnan, China, a place known to have some of the richest and most diverse bioresources in the world. This is one of the most favored edible mushrooms, due to its flavor. Our s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538b08cb138abf283d77a9f2688d94b6
https://pubmed.ncbi.nlm.nih.gov/18451502
https://pubmed.ncbi.nlm.nih.gov/18451502