Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kouichi Kurose"'
Autor:
Yuki Kondo, Takahiro Iwao, Sachimi Yoshihashi, Kayo Mimori, Ruri Ogihara, Kiyoshi Nagata, Kouichi Kurose, Masayoshi Saito, Takuro Niwa, Takayoshi Suzuki, Naoki Miyata, Shigeru Ohmori, Katsunori Nakamura, Tamihide Matsunaga
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104010 (2014)
In this study, we aimed to elucidate the effects and mechanism of action of valproic acid on hepatic differentiation from human induced pluripotent stem cell-derived hepatic progenitor cells. Human induced pluripotent stem cells were differentiated i
Externí odkaz:
https://doaj.org/article/3b19b0f151fd40d29f54261d116ecce7
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(11)
Recently, alternatives to animal testing have been used to evaluate skin sensitisers in cosmetic products. However, testing is still complicated and expensive. To develop a simpler, cost-effective and more accurate evaluation method for the skin sens
Publikováno v:
NIPPON SUISAN GAKKAISHI. 83:777-784
Autor:
Ryuichi Hasegawa, Hironobu Akao, Keiko Maekawa, Tatsuro Ishida, Yoshiro Saito, Kenji Takeda, Kouichi Kurose, Takashi Tanimoto, Keijiro Saku, Takashi Yamano, Kouji Kajinami, Kimie Sai, Aya Shiraki, Masafumi Ueno, Shusuke Yagi, Shunichi Miyazaki, Koichi Sugamura, Mizuho Iwadare, Ken-ichi Hirata, Masataka Sata, Yasuyuki Kawai, Koichi Node, Jun-ichi Oyama, Takuya Imatoh, Takashi Akasaka, Ryoko Sato-Ishida, Takeshi Soeki, Hisao Ogawa, Y. Matsuzawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 31:467-470
Statin-related myopathy (SRM) is a clinically important adverse reaction. Recent pharmacogenetic research, mainly in non-Asian populations, have indicated clinical relevance of some of genetic biomarkers to SRM, but predictive markers for SRM in Asia
Autor:
Shintaro, Suzuki, Yoshito, Miyata, Megumi, Jinno, Yasunari, Kishino, Tetsuya, Homma, Shin, Ota, Akihiko, Tanaka, Takuya, Yokoe, Tsukasa, Ohnishi, Hironori, Sagara, Naomi, Kurata, Kuniyoshi, Shimakura, Kouichi, Kurose
Publikováno v:
Arerugi = [Allergy]. 66(6)
A 35-year-old female, professional diver, reported nausea, vomiting, and systemic hives 20 to 30 minutes after ingestion of antipasto made with jellyfish. Patient reported prior episodes of swelling after stings from several different creatures, incl
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 44:89-94
Autor:
Junichi Azuma, Ryuichi Hasegawa, Gaku Okugawa, Masaki Kato, Toshihiko Kinoshita, Toru Kurosawa, Masataka Wakeno, Kazuya Ishiwata, Kouichi Kurose, Jun Nishikawa, Shinpei Nonen, Yoshiro Saito, Kazuyuki Hiratsuka
Publikováno v:
Psychiatry Research. 198:424-429
Sexual dysfunction is a major side effect of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs). We conducted a genome-wide association study to identify the genetic factors contributing to the ris
Autor:
Haruhiro Okuda, Hiroshi Nokihara, Kimie Sai, Yuichiro Ohe, Toru Kawanishi, Ikuo Sekine, Chikako Yomota, Noboru Yamamoto, Yasuhiro Matsumura, Hideo Kunitoh, Mikihiko Naito, Teruhiko Yoshida, Nagahiro Saijo, Tomohide Tamura, Tomoko Nishimaki-Mogami, Noriko Katori, Yoshiro Saito, Hiromi Fukushima-Uesaka, Jun-ichi Sawada, Kouichi Kurose
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4546-4559
Alpha‐1‐acid glycoprotein (AGP) encoded by orosomucoid genes ( ORM1 and ORM2 ) is an acute‐phase response protein and functions as a drug‐binding protein that affects pharmacokinetics (PK)/pharmacodynamics of binding drugs. To explore the eff
Autor:
Chie Sotozono, Michiko Aihara, R Hasegawa, Mayumi Ueta, Zenro Ikezawa, Masamichi Abe, Shigeru Kinoshita, Masahiro Tohkin, Yoshiro Saito, Kouichi Kurose, Masaaki Muramatsu, Hirokazu Furuya, Yukitoshi Takahashi, Kayoko Matsunaga, E Sugiyama, Jun Nishikawa, H Ikeda, Nahoko Kaniwa
Publikováno v:
The Pharmacogenomics Journal. 13:60-69
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe, cutaneous adverse drug reactions that are rare but life threatening. Genetic biomarkers for allopurinol-related SJS/TEN in Japanese were examined in a genome-wide associati
Publikováno v:
Molecular Genetics and Metabolism. 102:91-98
P-glycoprotein (P-gp), the product of the MDR1 gene, shows large interindividual variations in expression, which leads to differences in the pharmacokinetics of the substrate drugs. The functions of single nucleotide polymorphisms located in the nucl