Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kouichi Ikai"'
Autor:
Kouichi Ikai
Publikováno v:
Journal of Dermatological Science. 21:135-146
Arachidonic acid (5.8,11,14-eicosatetraenoic acid C20:4, n-6) is released from the cell membrane by the action of phospholipases on membrane phospholipids. Metabolites of arachidonic acid, which are generically termed eicosanoids, including prostagla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7e59034ab878101b0d4dd91d6a03f5
https://doi.org/10.1016/s0923-1811(99)00042-0
https://doi.org/10.1016/s0923-1811(99)00042-0
Autor:
Norihisa Matsuyoshi, M.S. Sasaki, K. Ohta, Chikako Nishigori, Hiroyuki Okamoto, Sadao Imamura, Kouichi Ikai, Kazumasa Morita
Publikováno v:
British Journal of Dermatology. 136:620-623
Two cases of Werner's syndrome are reported. Fibroblasts derived from both patients revealed reduced population doubling numbers. Chromosomal analyses for fibroblasts from both patients and lymphocytes from one patient revealed that chromosomal aberr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb7e323193fb26c673cb074cb461c23
https://doi.org/10.1046/j.1365-2133.1997.6301592.x
https://doi.org/10.1046/j.1365-2133.1997.6301592.x
Publikováno v:
Archives of Dermatological Research. 288:168-172
We examined the enzymatic activity of leukotriene (LT) A4 hydrolase, which catalyzes the conversion of LTA4 to LTB4, in peripheral leukocytes of patients with atopic dermatitis. The patients were divided into three categories (severe, moderate and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca56ee2e757abdce6d146d4de22d2345
https://doi.org/10.1007/bf02505219
https://doi.org/10.1007/bf02505219
Publikováno v:
Journal of Dermatological Science. 8:103-109
We examined the role of rho gene products ( rho proteins) on cell growth and cytoskeleton organization in transformed human epidermal cells in culture (HSC-1), using recombinant botulinum C3 exoenzyme which specifically ADP-ribosylates rho proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ebfb781b4d13e85ffec481553e1ed0
https://doi.org/10.1016/0923-1811(94)90003-5
https://doi.org/10.1016/0923-1811(94)90003-5
Autor:
Ikuko Furukawa, Motoaki Ozaki, Kouichi Ikai, Mayumi Fujita, Atsuhiko Ogino, Ken-ichi Toda, Sadao Imamura
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 3:59-62
Background Eosinophil cationic protein (ECP) is a highly basic protein (pI over 11) with molecular weight ranging from 18.5 to 22 kDa, and is released upon eosinophil activation. ECP is stored in the eosinophil granules and has potent bactericidal, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5629a27a7c74d5ad4dcf4e286983d67
https://doi.org/10.1111/j.1468-3083.1994.tb00072.x
https://doi.org/10.1111/j.1468-3083.1994.tb00072.x
Publikováno v:
Journal of Investigative Dermatology. 101(2):191-195
The importance of environmental factors such as ultraviolet light and temperature in the pathogenesis of cutaneous lupus erythematosus is well recognized. Recent evidence suggests the presence of autoantibodies to heat shock proteins (HSP) in the ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd0aeb3a9e412ff1c961f5385c2ef4a
Publikováno v:
Journal of Investigative Dermatology. 98(6):890-894
Cyclopentenone prostaglandins (PG) such as delta 12-PGJ2 and PGA are potent inhibitors of growth in a variety of cultured cells, including human epidermal cells. To clarify the mechanism of PG cytotoxicity in human epidermal cells, we examined the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cbb90b89cb93eaf5a8b2898b2cd435
Autor:
M. Besnard, John M. Wood, Mark R. Pittelkow, Kouichi Ikai, Karin U. Schallreuter, Masanori Fukushima, C. Dupont, J. Wepierre, F. Auclair, Norman D. Weiner, K. Egbaria, Rie Sone, Chandrasekharan Ramachandran, T. Grebe
Publikováno v:
Skin Pharmacology and Physiology. 4:45-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0d17648d15cdf4f42ffb391a29460b1
https://doi.org/10.1159/000210922
https://doi.org/10.1159/000210922
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 24:251-255
The activity of poly(adenosine diphosphate-ribose) (poly(ADP-ribose)) synthesis was examined in permeabilized transformed mouse epidermal cells (PAM 212 cells) in culture. PAM cells grown in low (0.02mM) Ca++ medium showed a higher activity of poly(A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43bbae66fe3617a13008e42d9cca540
https://doi.org/10.1267/ahc.24.251
https://doi.org/10.1267/ahc.24.251
Autor:
Motoaki Ozaki, Shigetoshi Sayama, Toshiyuki Aoshima, Tsuneo Mitani, Ikuko Furukawa, Sadao Imamura, Mitsuyoshi Omoto, Masami Uehara, Naoko Nakajima, Mari Sawami, Kouichi Ikai
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 9:54-56
We evaluated the serum levels of major basic protein (MBP), assayed using an MBP radioimmunoassay kit, and the effect of an anti-allergic agent, ketotifen, which has strong anti-eosinophil activity, in 56 atopic dermatitis (AD) patients. The serum MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017418d7e8271dd95ddb10bd9d678a71
https://doi.org/10.1016/s0926-9959(97)00633-8
https://doi.org/10.1016/s0926-9959(97)00633-8