Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Kouichi, Itoh"'
Autor:
Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel, Yasuhiro Ishihara
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important role in neuronal damage
Externí odkaz:
https://doaj.org/article/0b534191fd854352af87eb926b3f7659
Autor:
Yasuhiro Ishihara, Tatsuya Honda, Nami Ishihara, Kaede Namba, Makiko Taketoshi, Yoko Tominaga, Mayumi Tsuji, Christoph F. A. Vogel, Takeshi Yamazaki, Kouichi Itoh, Takashi Tominaga
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Valproic acid (VPA) is a clinically used antiepileptic drug, but it is associated with a significant risk of a low verbal intelligence quotient (IQ) score, attention-deficit hyperactivity disorder and autism spectrum disorder in c
Externí odkaz:
https://doaj.org/article/abd2015abb394a0c8823290ebad2e5bc
Autor:
Kenta Sakai, Fuyuko Takata, Gaku Yamanaka, Miho Yasunaga, Kana Hashiguchi, Kazuki Tominaga, Kouichi Itoh, Yasufumi Kataoka, Atsushi Yamauchi, Shinya Dohgu
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 155-165 (2021)
In this study, among neurovascular unit (NVU) cells, we focused on pericyte reactivity in mice subjected to controlled cortical impact (CCI) to understand how traumatic brain injury (TBI) causes uncoordinated crosstalk in the NVU and alters neuronal
Externí odkaz:
https://doaj.org/article/cc66b0bede0d4aedae7bd73d13ca81ea
Autor:
Rie Komori, Taira Matsuo, Aya Yokota-Nakatsuma, Ritsuka Hashimoto, Shizuka Kubo, Chihiro Kozawa, Tomomi Kono, Yasuhiro Ishihara, Kouichi Itoh
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7608 (2022)
Levetiracetam (LEV) suppresses the upregulation of proinflammatory molecules that occurs during epileptogenesis after status epilepticus (SE). Based on previous studies, LEV likely helps prevent the onset of epilepsy after insults to the brain, unlik
Externí odkaz:
https://doaj.org/article/c3718ebc414f4d378625a3b7907ac6e5
Autor:
Taira Matsuo, Rie Komori, Minami Nakatani, Shiori Ochi, Aya Yokota-Nakatsuma, Junichi Matsumoto, Fuyuko Takata, Shinya Dohgu, Yasuhiro Ishihara, Kouichi Itoh
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7671 (2022)
Acute brain inflammation after status epilepticus (SE) is involved in blood–brain barrier (BBB) dysfunction and brain edema, which cause the development of post-SE symptomatic epilepsy. Using pilocarpine-induced SE mice, we previously reported that
Externí odkaz:
https://doaj.org/article/b352fb23729243408e761683dd95d61f
Autor:
Yasuhiro Ishihara, Kouichi Itoh
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 72:23-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2099cf440fee8d9c589af8ef1053864a
https://doi.org/10.3164/jcbn.22-71
https://doi.org/10.3164/jcbn.22-71
Autor:
Kouji Niidome, Ruri Taniguchi, Takeshi Yamazaki, Mayumi Tsuji, Kouichi Itoh, Yasuhiro Ishihara
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10962 (2021)
We previously showed that the antiepileptic drug levetiracetam (LEV) inhibits microglial activation, but the mechanism remains unclear. The purpose of this study was to identify the target of LEV in microglial activity suppression. The mouse microgli
Externí odkaz:
https://doaj.org/article/94e06825f47c4ca6a7a0934cbc48e9a6
Autor:
Yasuhiro Ishihara, Kouichi Itoh, Miki Tanaka, Mayumi Tsuji, Toshihiro Kawamoto, Suguru Kawato, Christoph F. A. Vogel, Takeshi Yamazaki
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Several studies have shown that docosahexaenoic acid (DHA) attenuates epileptic seizures; however, the molecular mechanism by which it achieves this effect is still largely unknown. DHA stimulates the retinoid X receptor, which reportedly re
Externí odkaz:
https://doaj.org/article/f622cc0973304afc8cc9c6885c665567
Autor:
Miki Tanaka, Masaho Fujikawa, Ami Oguro, Kouichi Itoh, Christoph F. A. Vogel, Yasuhiro Ishihara
Publikováno v:
Cells, Vol 10, Iss 4, p 718 (2021)
Microglia are activated after ischemic stroke and induce neuroinflammation. The expression of the aryl hydrocarbon receptor (AhR) has recently been reported to elicit cytokine expression. We previously reported that microglial activation mediates isc
Externí odkaz:
https://doaj.org/article/1db9b7f785d14e2faa0897f98837cbc5
Publikováno v:
Journal of Medical Ultrasonics (2001)
The concept of point-of-care ultrasound has been widely accepted owing to the development of portable ultrasound systems and growing body of evidence concerning its extensive utility. Thus, it is reasonable to suggest that training to use this modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7cd29b7dc3c6740ff07175b8a71932
https://doi.org/10.1007/s10396-021-01178-z
https://doi.org/10.1007/s10396-021-01178-z