Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies.

Autor: Olešová D; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Dobešová D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic., Majerová P; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Brumarová R; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic., Kvasnička A; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic., Kouřil Š; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic., Stevens E; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Hanes J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Fialová Ľ; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Michalicová A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Piešťanský J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Šinský J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic., Kaňovský P; Department of Neurology, University Hospital Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.; Department of Neurology, Palacky University, Zdravotníků 7, Olomouc, 779 00, Czech Republic., Friedecký D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic. david.friedecky@upol.cz., Kováč A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic. andrej.kovac@savba.sk.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 27; Vol. 21 (1), pp. 78. Date of Electronic Publication: 2024 Mar 27.

Metabolomic, Lipidomic and Proteomic Characterisation of Lipopolysaccharide-induced Inflammation Mouse Model.

Autor: Puris E; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany. Electronic address: elena.puris@uni-heidelberg.de., Kouřil Š; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900 Olomouc, Czech Republic., Najdekr L; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic., Auriola S; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Loppi S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Department of Immunobiology, University of Arizona, 1656 E Mabel Street, Tucson, AZ 85724-5221, United States., Korhonen P; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Gómez-Budia M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Friedecký D; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900 Olomouc, Czech Republic., Gynther M; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany.

Publikováno v: Neuroscience [Neuroscience] 2022 Aug 01; Vol. 496, pp. 165-178. Date of Electronic Publication: 2022 May 28.

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice.

Autor: Puris E; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland. elena.puris@uni-heidelberg.de.; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120, Heidelberg, Germany. elena.puris@uni-heidelberg.de., Kouřil Š; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900, Olomouc, Czech Republic.; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900, Olomouc, Czech Republic., Najdekr L; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900, Olomouc, Czech Republic., Loppi S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.; Department of Immunobiology, University of Arizona, 1656 E Mabel Street, Tucson, AZ, 85724-5221, USA., Korhonen P; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland., Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland., Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.; Neuroscience Center, Helsinki Institute for Life Science, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland., Friedecký D; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900, Olomouc, Czech Republic.; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900, Olomouc, Czech Republic., Gynther M; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.

Publikováno v: Scientific reports [Sci Rep] 2021 Jun 22; Vol. 11 (1), pp. 13076. Date of Electronic Publication: 2021 Jun 22.

A newborn screening approach to diagnose 3-hydroxy-3-methylglutaryl-CoA lyase deficiency.

Autor: Václavík J; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Mádrová L; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Kouřil Š; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., de Sousa J; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic.; Department of Mathematical Analysis and Applications of Mathematics, Faculty of Science Palacký University Olomouc Olomouc Czech Republic., Brumarová R; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Janečková H; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Jáčová J; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Friedecký D; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic., Knapková M; Banská Bystrica Children's University Hospital Banská Bystrica Slovakia., Kluijtmans LAJ; Translational Metabolic Laboratory, Department of Laboratory Medicine Radboud University Medical Centre GA Nijmegen Netherlands., Grünert SC; Department of General Pediatrics, Adolescent Medicine and Neonatology Medical Center - University of Freiburg, Faculty of Medicine Freiburg Germany., Vaz FM; Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry Amsterdam Netherlands., Janzen N; Screening-Labor Hannover Hannover Germany.; Department of Clinical Chemistry Hannover Medical School Hannover Germany., Wanders RJA; Laboratory Genetic Metabolic Diseases, Department of Clinical Chemistry Amsterdam Netherlands., Wevers RA; Translational Metabolic Laboratory, Department of Laboratory Medicine Radboud University Medical Centre GA Nijmegen Netherlands., Adam T; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc Olomouc Czech Republic.; Laboratory of Inherited Metabolic Disorders, Department of Clinical Chemistry University Hospital in Olomouc Olomouc Czech Republic.

Publikováno v: JIMD reports [JIMD Rep] 2020 Apr 14; Vol. 54 (1), pp. 79-86. Date of Electronic Publication: 2020 Apr 14 (Print Publication: 2020).

Neuroinflammaging: A Tight Line Between Normal Aging and Age-Related Neurodegenerative Disorders.

Autor: Soraci, Luca¹, Corsonello, Andrea^1,2, Paparazzo, Ersilia³, Montesanto, Alberto³, Piacenza, Francesco⁴, Olivieri, Fabiola^5,6, Gambuzza, Maria Elsa⁷ me.gambuzza@sanita.it, Savedra, Edlin Villalta⁸, Marino, Silvia⁹, Lattanzio, Fabrizia¹⁰, Biscetti, Leonardo¹¹

Publikováno v: Aging & Disease. Aug2024, Vol. 15 Issue 4, p1726-1747. 22p.