Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection

Autor: Dillon, SM, Lee, EJ, Kotter, CV, Austin, GL, Gianella, S, Siewe, B, Smith, DM, Landay, AL, McManus, MC, Robertson, CE, Frank, DN, McCarter, MD, Wilson, CC

Publikováno v: Dillon, SM; Lee, EJ; Kotter, CV; Austin, GL; Gianella, S; Siewe, B; et al.(2016). Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection.. Mucosal immunology, 9(1), 24-37. doi: 10.1038/mi.2015.33. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/08z8k8cp

HIV-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. Dendritic cells (DCs) are crucial in maintaining intestinal homeostasis, but the impact of HIV-1 infection on intestin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::91866354b578cc46360ebd8415148832
http://www.escholarship.org/uc/item/08z8k8cp

Whole-Genome Sequencing Identifies In Vivo Acquisition of a blaCTX-M-27-Carrying IncFII Transmissible Plasmid as the Cause of Ceftriaxone Treatment Failure for an Invasive Salmonella enterica Serovar Typhimurium Infection.

Autor: McCollister B; University of Colorado Anschutz Medical Campus, Division of Infectious Disease, Aurora, Colorado, USA., Kotter CV; University of Colorado Anschutz Medical Campus, Division of Infectious Disease, Aurora, Colorado, USA., Frank DN; University of Colorado Anschutz Medical Campus, Division of Infectious Disease, Aurora, Colorado, USA., Washburn T; University of Colorado Anschutz Medical Campus, Division of Infectious Disease, Aurora, Colorado, USA., Jobling MG; University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA michael.jobling@ucdenver.edu.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2016 Nov 21; Vol. 60 (12), pp. 7224-7235. Date of Electronic Publication: 2016 Nov 21 (Print Publication: 2016).

Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection.

Autor: Dillon SM; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Lee EJ; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Kotter CV; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Austin GL; Department of Gastroenterology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Gianella S; Division of Infectious Diseases, University of California San Diego, La Jolla, California, USA., Siewe B; Department of Immunology-Microbiology, Rush University Medical Center, Chicago, Illinois, USA., Smith DM; Division of Infectious Diseases, University of California San Diego, La Jolla, California, USA., Landay AL; Department of Immunology-Microbiology, Rush University Medical Center, Chicago, Illinois, USA., McManus MC; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Robertson CE; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; University of Colorado Microbiome Research Consortium, Aurora, Colorado, USA., Frank DN; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; University of Colorado Microbiome Research Consortium, Aurora, Colorado, USA., McCarter MD; Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Wilson CC; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2016 Jan; Vol. 9 (1), pp. 24-37. Date of Electronic Publication: 2015 Apr 29.

A "CLEAN CASE" OF SYSTEMIC INJURY: MESENTERIC LYMPH AFTER HEMORRHAGIC SHOCK ELICITS A STERILE INFLAMMATORY RESPONSE.

Autor: Yi J; Department of Surgery †Division of Infectious Diseases, University of Colorado Denver ‡Department of Surgery, Denver Health Medical Center, Denver, Colorado §Department of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts ||Children's Hospital of Colorado, Denver, Colorado., Slaughter A, Kotter CV, Moore EE, Hauser CJ, Itagaki K, Wohlauer M, Frank DN, Silliman C, Banerjee A, Peltz E

Publikováno v: Shock (Augusta, Ga.) [Shock] 2015 Oct; Vol. 44 (4), pp. 336-40.

Intestinal lesions are associated with altered intestinal microbiome and are more frequent in children and young adults with cystic fibrosis and cirrhosis.

Autor: Flass T; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America., Tong S; Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital, Aurora, Colorado, United States of America., Frank DN; Department of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America., Wagner BD; Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital, Aurora, Colorado, United States of America; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, United States of America., Robertson CE; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, United States of America., Kotter CV; Department of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America., Sokol RJ; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America; Colorado Clinical and Translational Sciences Institute, University of Colorado School of Medicine, Aurora, CO, United States of America., Zemanick E; Section of Pediatric Pulmonary Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America., Accurso F; Section of Pediatric Pulmonary Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America., Hoffenberg EJ; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America., Narkewicz MR; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States of America.

Publikováno v: PloS one [PLoS One] 2015 Feb 06; Vol. 10 (2), pp. e0116967. Date of Electronic Publication: 2015 Feb 06 (Print Publication: 2015).