Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kotomi Sugawara"'
Autor:
Kumi Ubukawa, Isuzu Kobayashi, Hideki Mochizuki, Wataru Nunomura, Kotomi Sugawara, Naoto Takahashi, Hideki Wakui, Eri H. Hayakawa, Katsuya Araki, Kenichi Sawada
Publikováno v:
International Journal of Hematology. 108:130-138
Although the neuronal protein α-synuclein (α-syn) is thought to play a central role in the pathogenesis of Parkinson's disease (PD), its physiological function remains unknown. It is known that α-syn is also abundantly expressed in erythrocytes. H
Autor:
Hideki Wakui, Mika Yonezawa, Tatsufumi Goto, Mizuki Nakagawa, Kotomi Sugawara, Wataru Nunomura, Shigeyoshi Nakamura, Shun-ichi Kidokoro
Publikováno v:
Journal of Biochemistry. 160:299-308
It is widely believed that enzymatic activities in ectothermic organisms adapt to environmental temperatures. However, to date, no study has thoroughly compared multiple thermodynamic enzymatic characteristics across species living in dramatically di
Publikováno v:
Biochemical and Biophysical Research Communications. 473:999-1004
Hydroxychloroquine (HCQ) is a widely used drug in the treatment of autoimmune diseases, such as arthritis and systemic lupus erythematosus. It has also been prescribed for the treatment of malaria owing to its lower toxicity compared to its closely r
Autor:
Mika Yonezawa, Wataru Nunomura, Shun-ichi Kidokoro, Hideki Wakui, Kotomi Sugawara, Mizuki Nakagawa, Shigeyoshi Nakamura
Publikováno v:
Fisheries Science. 82:519-527
Vertebrates have three genes (LDHA, LDHB, and LDHC) encoding skeletal muscle-, heart muscle- and testis-specific lactate dehydrogenase (LDH, E.C. 1.1.1.27), respectively. The muscle and heart LDHs are tetramers formed by polypeptides encoded by LDHA
Autor:
Wataru Nunomura, Hideki Wakui, Tatsufumi Goto, Kenichi Sawada, Kumi Ubukawa, Naoto Takahashi, Isuzu Kobayashi, Yong-Mei Guo, Ken Asanuma, Yumi Sasaki, Kotomi Sugawara
Publikováno v:
Experimental Hematology. 72:14-26.e1
More than 2million human erythroblasts extrude their nuclei every second in bone marrow under hypoxic conditions (7% O
Autor:
Hideki Wakui, Wataru Nunomura, Tatsufumi Goto, Shigeyoshi Nakamura, Kotomi Sugawara, Shun-ichi Kidokoro
Publikováno v:
Biochemical and biophysical research communications. 479(4)
Lactate dehydrogenase (LDH) is a glycolytic enzyme that catalyzes the final step of glycolysis and produces NAD+. In somatic cells, LDH forms homotetramers and heterotetramers that are encoded by two different genes: LDHA (skeletal muscle type, M) an
Autor:
Isuzu Kobayashi, Ken Asanuma, Wataru Nunomura, Kumi Ubukawa, Kenichi Sawada, Kotomi Sugawara, Junsuke Yamashita, Naoto Takahashi, Yong-Mei Guo
Publikováno v:
Experimental Hematology. 44:247-256.e12
Mammalian erythroblasts undergo enucleation through a process thought to be similar to cytokinesis. Microtubule-organizing centers (MTOCs) mediate organization of the mitotic spindle apparatus that separates the chromosomes during mitosis and are kno
Autor:
Mika Yonezawa, Mizuki Nakagawa, Shigeyoshi Nakamura, Tatsufumi Goto, Kotomi Sugawara, Shun-Ichi Kidokoro, Hideki Wakui, Wataru Nunomura
Publikováno v:
Journal of Biochemistry; Nov2016, Vol. 160 Issue 5, p299-308, 10p, 2 Charts, 7 Graphs