Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival.

Autor: Kotnik, Emilee N.^1,2,3 (AUTHOR), Mullen, Mary M.^1,2,3 (AUTHOR), Spies, Nicholas C.^3,4 (AUTHOR), Li, Tiandao⁵ (AUTHOR), Inkman, Matthew⁶ (AUTHOR), Zhang, Jin⁶ (AUTHOR), Martins-Rodrigues, Fernanda⁷ (AUTHOR), Hagemann, Ian S.^1,2,3,4 (AUTHOR), McCourt, Carolyn K.^1,2,3 (AUTHOR), Thaker, Premal H.^1,2,3 (AUTHOR), Hagemann, Andrea R.^1,2,3 (AUTHOR), Powell, Matthew A.^1,2,3 (AUTHOR), Mutch, David G.^1,2,3 (AUTHOR), Khabele, Dineo^1,2,3 (AUTHOR), Longmore, Gregory D.^7,8 (AUTHOR), Mardis, Elaine R.⁹ (AUTHOR), Maher, Christopher A.^7,10,11,12 (AUTHOR), Miller, Christopher A.⁷ (AUTHOR), Fuh, Katherine C.^1,2,3,13 (AUTHOR) katherine.fuh@ucsf.edu

Publikováno v: Communications Biology. 7/3/2023, Vol. 6 Issue 1, p1-11. 11p.

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

Autor: Kotnik, Emilee N, Mullen, Mary M, Spies, Nicholas C, Li, Tiandao, Inkman, Matthew, Zhang, Jin, Martins-Rodrigues, Fernanda, Hagemann, Ian S, McCourt, Carolyn K, Thaker, Premal H, Hagemann, Andrea R, Powell, Matthew A, Mutch, David G, Khabele, Dineo, Longmore, Gregory D, Mardis, Elaine R, Maher, Christopher A, Miller, Christopher A, Fuh, Katherine C

Publikováno v: Communications biology, vol 6, iss 1

High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significantly improv

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https://escholarship.org/uc/item/9gq374mg

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