Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kothari Sanjeev H"'
Autor:
Radha R. Vippagunta, Kothari Sanjeev H
Publikováno v:
Molecular Pharmaceutics. 16:943-951
The conformational flexibility of organic molecules introduces more structural options for crystallization to occur but has potential complications, such as, reduced crystallization tendency and conformational polymorphism. Although a variety of ener
Publikováno v:
Powder Technology. 331:1-6
Mechanical properties of pharmaceutical materials, e.g., Young's modulus (E), indentation hardness (H), and tensile strength (σt), play an important role in powder compaction process. However, few studies investigated the relationship among these pa
Publikováno v:
In International Journal of Pharmaceutics 2002 232(1):69-80
Autor:
Kumar, Vijay *, Kothari, Sanjeev H.
Publikováno v:
In International Journal of Pharmaceutics 1999 177(2):173-182
Publikováno v:
Computers & Chemical Engineering. 34:1049-1057
Very limited work has been reported on comparing the performance of the roller compaction process at different scales. The majority of the approaches highlighted in the literature discuss the applicability of using confined uniaxial compaction for pr
Publikováno v:
Powder Technology. 195:15-24
The purpose of this study was to evaluate the influences of intrinsic drug mechanical properties and different granulation binder delivery processes on the physical and mechanical properties of high drug load granulations after wet granulation. Formu
Publikováno v:
International Journal of Pharmaceutics. 354:77-81
Capsule formulations of two drugs under development showed slower dissolution upon storage; Drug A, after 2.5 weeks at 40 degrees C/23% RH and 4 weeks at 30 degrees C/60% RH, and Drug B, after 6 weeks at 50 degrees C and 40 degrees C/75% RH. The form
Publikováno v:
Molecular pharmaceutics. 12(7)
The purpose of this study was to identify and characterize precipitates obtained from a liquid formulation of GNE068.HCl, a Genentech developmental compound, and lipophilic excipients, such as propylene glycol monocaprylate, and monolaurate. Precipit
Autor:
D. Li, Divyakant Desai, Douglas Both, M. Lai, F. Rinaldi, Srinivasa Paruchuri, Simon S M Fung, Kothari Sanjeev H
Publikováno v:
International Journal of Pharmaceutics. 308:40-45
Hydrochlorothiazide (HCTZ) 60 mg strength tablets containing commonly used excipients and hydroxypropyl cellulose, marketed as either Klucel-EF (HPC, NF from Hercules, USA) or HPC-L (HPC, NF from Nippon Soda, Japan), as a binder were manufactured usi
Publikováno v:
International Journal of Pharmaceutics. 232:69-80
The purpose of this study was to examine and compare the powder and mechanical properties of different batches of low crystallinity powdered cellulose (LCPC-S1 to LCPC-S5) with those of commercial microcrystalline celluloses (MCC) (Avicel PH-101, Avi