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pro vyhledávání: '"Kotesvar Rao"'
Autor:
Han-Zhong Zhang, Eva Papp, John C. Wu, Kotesvar Rao, Kenneth Straub, Stephen F. Carr, Josef Fried
Publikováno v:
Journal of Medicinal Chemistry. 40:4-8
Functionalized 2-alkyl derivatives of inosinic acid have been synthesized to serve as reversible as well as irreversible inhibitors of the human type II enzyme inosine monophosphate dehydrogenase. These compounds were designed to react with Cys-331 o