Výsledky vyhledávání - "Koteshwara Rao Valasani"

Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea

Autor: Koteshwara Rao Valasani, Kavisha Arora, Sunitha Yarlagadda, Randal K. Buddington, Aixia Ren, Hugo R. de Jonge, Mohamed T. Shata, Kaushik Parthasarathi, Koryse Woodrooffe, Shiva Kumar Shanmukhappa, Chandrima Sinha, Weiqiang Zhang, John D. Schuetz, Changsuk Moon, Anjaparavanda P. Naren

Publikováno v: Journal of Biological Chemistry, 290(18), 11246-11257. American Society for Biochemistry and Molecular Biology Inc.

Diarrhea is one of the most common adverse side effects observed in similar to 7% of individuals consuming Food and Drug Administration (FDA)-approved drugs. The mechanism of how these drugs alter fluid secretion in the gut and induce diarrhea is not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e724f2eddd3207d1e6a5725ebe68ea1
https://doi.org/10.1074/jbc.m114.605410

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