Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kotaro Tokumoto"'
Autor:
Hiroshi Hamamoto, Suresh Panthee, Atmika Paudel, Kenichi Ishii, Jyunichiro Yasukawa, Jie Su, Atsushi Miyashita, Hiroaki Itoh, Kotaro Tokumoto, Masayuki Inoue, Kazuhisa Sekimizu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. Here, the authors show that the antimicrobial activity of lysocin E is potentiated through interactions with host serum proteins (such as apolipo
Externí odkaz:
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
Autor:
Hiroaki Itoh, Kotaro Tokumoto, Takuya Kaji, Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu, Masayuki Inoue
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The depsipeptide Lysocin E has antibacterial activity against methicillin-resistant Staphylococcus aureus. Here, the authors developed a high-throughput one-bead-on-compound method for the synthesis and screening lysocin E derivatives, with several h
Externí odkaz:
https://doaj.org/article/24ce67f6d8c4465eab7275eeeed39cad
Autor:
Jie Su, Atmika Paudel, Jyunichiro Yasukawa, Kazuhisa Sekimizu, Hiroshi Hamamoto, Suresh Panthee, Atsushi Miyashita, Hiroaki Itoh, Masayuki Inoue, Kenichi Ishii, Kotaro Tokumoto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. For unclear reasons, the antibacterial activity of lysocin E in a mouse systemic infection model is higher than expected from in vitro results, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b6078172ae48fc2ac70d0ae9a65f52
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
https://doaj.org/article/b0d96c9f5e974962964e3a02e7b2c23b
Autor:
Kenichi Ishii, Kotaro Tokumoto, Atmika Paudel, Kazuhisa Sekimizu, Jyunichiro Yasukawa, Hiroshi Hamamoto, Hiroaki Itoh, Masayuki Inoue, Su Jie, Suresh Panthee
The development of antimicrobials that exert therapeutic efficacy by novel mechanisms is crucial toward combatting multidrug-resistant bacteria. We previously reported a novel antibiotic, lysocin E, that is effective against methicillin-resistant Sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8287d09dac9de59a72c25fe4fb75afe7
https://doi.org/10.21203/rs.3.rs-89037/v1
https://doi.org/10.21203/rs.3.rs-89037/v1
Autor:
Atmika Paudel, Takuya Kaji, Hiroshi Hamamoto, Kotaro Tokumoto, Hiroaki Itoh, Suresh Panthee, Kazuhisa Sekimizu, Masayuki Inoue
Publikováno v:
The Journal of organic chemistry. 83(13)
WAP-8294A2 (lotilibcin, 1) is a potent antibiotic with superior in vivo efficacy to vancomycin against methicillin-resistant Staphylococcus aureus (MRSA). Despite the great medical importance, its molecular mode of action remains unknown. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6476ebec7a997b3a6ff40e1df668a3a8
https://pubmed.ncbi.nlm.nih.gov/29019678
https://pubmed.ncbi.nlm.nih.gov/29019678