Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kotaro Shinpo"'
Autor:
Tsuneyoshi Tanabe, Masaya Takeuchi, Masako Sakanoue, Satoru Kamada, Mieko Iwata, Kotaro Shinpo
Publikováno v:
The Journal of Toxicological Sciences. 9:13-28
The effects of ranitidine hydrochloride, a histamine H2-receptor antagonist, on the reproductivity of male and female rats of Crj : CD (SD) strain and the development of their fetuses were examined. Ranitidine hydrochloride was intravenously administ
Autor:
Satoru Kamada, Masaya Takeuchi, Seiichi Imoto, Jun-ichi Sudo, Akiko Yahata, Kotaro Shinpo, Tsuneyoshi Tanabe, Megumi Kosaka
Publikováno v:
The Journal of Toxicological Sciences. 10:83-103
A teratogenicity study of halopredone acetate (THS-201), a synthetic corticosteroid, was carried out using Jcl: Wistar rats. Pregnant rats were treated subcutaneously in doses of 0.1, 0.5, 2.5 and 12.5 mg/kg/day, from day 7 to day 17 of gestation. Tw
Autor:
Jun-ichi Sudo, Seiichi Imoto, Megumi Kosaka, Tsuneyoshi Tanabe, Kotaro Shinpo, Masaya Takeuchi, Satoru Kamada, Akiko Yahata
Publikováno v:
The Journal of Toxicological Sciences. 10:71-81
A fertility study of halopredone acetate (THS-201), a synthetic corticosteroid, was carried out using Jcl: Wistar rats. Male rats were treated subcutaneously for 63 days before mating and throughout mating, and female rats were treated subcutaneously
Autor:
Ichiro Makita, Masaya Takeuchi, Shinichi Ohkuma, Takashi Hashi, Kotaro Shinpo, Hiroyuki Tanigawa, Hajime Shimazu, Kyoichi Takeda, Yukifumi Kokuba, Takeshi Yamazoe, Chiaki Onodera
Publikováno v:
The Journal of Toxicological Sciences. 5:33-57
Chronic toxicity of lentinan was studied in male and female JCL:SD rats. Lentinan was given intravenously into tail vein. Dosage levels employed were 0 (5% mannitol), 0.01, 0.1, 1 (with or without dextran), and 10 mg/kg/day for 6 months in a volume o
Autor:
Shuzo Okazaki, Mizue Ichinohe, Tomoko Tsuga, Masaya Takeuchi, Jun-ichi Sudo, Kotaro Shinpo, Tsuneyoshi Tanabe, Masayo Kaga
Publikováno v:
The Journal of Toxicological Sciences. 10:1-10
Since halopredone acetate (THS-201), a synthetic corticosteroid, is expected to be used clinically for intra-articular injections because of its long-lasting activity in the synovial bursa, its acute toxicity was compared with that of triamsinolone a
Autor:
Kotaro Shinpo, Nobuo Kusano
Publikováno v:
Pathology International. 14:189-209
Autor:
Satoru Kamada, Seiichi Imoto, Megumi Kosaka, Tsuneyoshi Tanabe, Kotaro Shinpo, Akiko Yahata, Masaya Takeuchi, Jun-ichi Sudo
Publikováno v:
The Journal of toxicological sciences. 10
A peri- and postnatal study of halopredone acetate (THS-201), a synthetic corticosteroid, was carried out using Jcl: Wistar rats. Pregnant rats were treated subcutaneously in doses of 0.05, 0.4, 3.2 and 25.6 mg/kg/day, from day 17 of gestation to day