Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Kotaro Saga"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract CRISPR-Cas9 system can be used to generate knock-out cancer cell lines. An insertion or deletion induced by a single guide RNA (gRNA) is often used to generate knock-out cells, however, some cells express the target gene by skipping the disr
Externí odkaz:
https://doaj.org/article/c58c601a2d084314b7457d9dbe85a4e8
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Human papillomavirus (HPV) 16 infection in the oropharynx is one of the major risk factors for oropharyngeal carcinoma. Although the HPV E6 and E7 proteins are known to have a role in head and neck carcinogenesis, whether their expression is
Externí odkaz:
https://doaj.org/article/4f6cff14c7fc4653b403efd855c272b5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/17dc1d0a90da484f814354f0a1856cb9
Autor:
Kotaro Saga, Jinhee Park, Keisuke Nimura, Norihiko Kawamura, Airi Ishibashi, Norio Nonomura, Yasufumi Kaneda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells,
Externí odkaz:
https://doaj.org/article/2c4071e46437497cb1567048792d7675
Autor:
Keisuke Nimura, Masamichi Yamamoto, Makiko Takeichi, Kotaro Saga, Katsuyoshi Takaoka, Norihiko Kawamura, Hirohisa Nitta, Hiromichi Nagano, Saki Ishino, Tatsuya Tanaka, Robert J Schwartz, Hiroyuki Aburatani, Yasufumi Kaneda
Publikováno v:
eLife, Vol 5 (2016)
Transcription factors organize gene expression profiles by regulating promoter activity. However, the role of transcription factors after transcription initiation is poorly understood. Here, we show that the homeoprotein Nkx2-5 and the 5’-3’ exon
Externí odkaz:
https://doaj.org/article/edbfe0b136dc4e7f952bb9f94f4c0f27
Autor:
Kei Takahashi, Masayuki Endo, Takekazu Miyoshi, Mitsuhiro Tsuritani, Yukiko Shimazu, Hiroshi Hosoda, Kotaro Saga, Katsuto Tamai, Alan W Flake, Jun Yoshimatsu, Tadashi Kimura
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123712 (2015)
OBJECTIVES:Induction of the immune response is a major problem in replacement therapies for inherited protein deficiencies. Tolerance created in utero can facilitate postnatal treatment. In this study, we aimed to induce immune tolerance towards a fo
Externí odkaz:
https://doaj.org/article/05ac6715862c454fac258723a5fdb564
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106661 (2014)
The orchestration of histone modifiers is required to establish the epigenomic status that regulates gene expression during development. Whsc1 (Wolf-Hirschhorn Syndrome candidate 1), a histone H3 lysine 36 (H3K36) trimethyltransferase, is one of the
Externí odkaz:
https://doaj.org/article/41829ca3ee494cccb1beb9bd2ccb760b
Autor:
Yasufumi Kaneda, Jun Luo, Mitsuhiro Arisawa, Norio Nonomura, Kyoso Ishida, Yusuke Yoshikawa, Hiromichi Nagano, Koji Kitamura, Airi Ishibashi, Kotaro Saga, Keisuke Nimura, Norihiko Kawamura
A list of antibodies used in the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e2d2cd8987d68d4bf08d42692cf1ac
https://doi.org/10.1158/0008-5472.22420928.v1
https://doi.org/10.1158/0008-5472.22420928.v1
PDF file - 103K, Measurement of the ZZ-scIL-12 on Fc-HVJ-E.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfec7041e2da2f0c710b9c068d1f2870
https://doi.org/10.1158/1078-0432.22451283
https://doi.org/10.1158/1078-0432.22451283