Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kotaro Hiraoka"'
Autor:
Michinori Ezura, Akio Kikuchi, Nobuyuki Okamura, Aiko Ishiki, Takafumi Hasegawa, Ryuichi Harada, Shoichi Watanuki, Yoshihito Funaki, Kotaro Hiraoka, Toru Baba, Naoto Sugeno, Shun Yoshida, Junpei Kobayashi, Michiko Kobayashi, Ohito Tano, Shun Ishiyama, Takaaki Nakamura, Ichiro Nakashima, Shunji Mugikura, Ren Iwata, Yasuyuki Taki, Katsutoshi Furukawa, Hiroyuki Arai, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Atsushi Takeda, Masashi Aoki
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Introduction: We aimed to determine whether in vivo tau deposits and monoamine oxidase B (MAO-B) detection using 18F-THK5351 positron emission tomography (PET) can assist in the differential distribution in patients with corticobasal syndrome (CBS),
Externí odkaz:
https://doaj.org/article/32c907a418364c868797fbcc1c7cd9a0
Autor:
Aiko Ishiki, Ryuichi Harada, Hideaki Kai, Naomi Sato, Tomoko Totsune, Naoki Tomita, Shoichi Watanuki, Kotaro Hiraoka, Yoichi Ishikawa, Yoshihito Funaki, Ren Iwata, Shozo Furumoto, Manabu Tashiro, Hironobu Sasano, Tetsuyuki Kitamoto, Yukitsuka Kudo, Kazuhiko Yanai, Katsutoshi Furukawa, Nobuyuki Okamura, Hiroyuki Arai
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Recent positron emission tomography (PET) studies have demonstrated the accumulation of tau PET tracer in the affected region of progressive supranuclear palsy (PSP) cases. To confirm the binding target of radiotracer in PSP, we performed an
Externí odkaz:
https://doaj.org/article/27689a71ca88485fb74afdca3053d8aa
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158153 (2016)
Pax6 is a transcription factor that pleiotropically regulates various developmental processes in the central nervous system. In a previous study, we revealed that Pax6 heterozygous mutant (rSey2/+) adult rats exhibit abnormalities in social interacti
Externí odkaz:
https://doaj.org/article/ab0dc9a790cd4d589ffbf207793001ad
Autor:
Samuel N Lockhart, Suzanne L Baker, Nobuyuki Okamura, Katsutoshi Furukawa, Aiko Ishiki, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo, Ryuichi Harada, Naoki Tomita, Kotaro Hiraoka, Shoichi Watanuki, William J Jagust
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158460 (2016)
[18F]THK5351, a recently-developed positron emission tomography (PET) tracer for measuring tau neurofibrillary tangle accumulation, may help researchers examine aging, disease, and tau pathology in living human brains. We examined THK5351 tracer phar
Externí odkaz:
https://doaj.org/article/de3b40b692504cc5bbdcf8deaa24a799
Autor:
Kelssy Hitomi dos Santos Kawata, Ryusaku Hashimoto, Yoshiyuki Nishio, Atsuko Hayashi, Nanayo Ogawa, Shigenori Kanno, Kotaro Hiraoka, Kayoko Yokoi, Osamu Iizuka, Etsuro Mori
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 29-37 (2012)
The aim of this study was to validate the Japanese version of the Addenbrooke’s Cognitive Examination-Revised (ACE-R) [Mori: Japanese Edition of Hodges JR’s Cognitive Assessment for Clinicians, 2010] designed to detect dementia, and to compare it
Externí odkaz:
https://doaj.org/article/dd6c0880476849e693e3378f1d19f724
Publikováno v:
Behavioural Neurology, Vol 21, Iss 3-4, Pp 187-192 (2009)
We report on a patient with visual agnosia for line drawings and silhouette pictures following cerebral infarction in the region of the right posterior cerebral artery. The patient retained the ability to recognize real objects and their photographs,
Externí odkaz:
https://doaj.org/article/e7596d634cac42ffb8955d83967c13d8
Autor:
Aiko Ishiki, Nobuyuki Okamura, Katsutoshi Furukawa, Shozo Furumoto, Ryuichi Harada, Naoki Tomita, Kotaro Hiraoka, Shoichi Watanuki, Yoichi Ishikawa, Tetsuro Tago, Yoshihito Funaki, Ren Iwata, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140311 (2015)
The formation of neurofibrillary tangles is believed to contribute to the neurodegeneration observed in Alzheimer's disease (AD). Postmortem studies have shown strong associations between the neurofibrillary pathology and both neuronal loss and the s
Externí odkaz:
https://doaj.org/article/3b5140ccc7a145508e94a1f08462a7a1
Dissertation/ Thesis
Autor:
Laarni Grace Corales, Hitoshi Inada, Kotaro Hiraoka, Shun Araki, Shinya Yamanaka, Takako Kikkawa, Noriko Osumi
Publikováno v:
Journal of anatomy. 241(3)
The subcommissural organ (SCO) is a part of the circumventricular organs located in the dorsocaudal region of the third ventricle at the entrance of the aqueduct of Sylvius. The SCO comprises epithelial cells and produces high molecular weight glycop
Publikováno v:
The Tohoku Journal of Experimental Medicine. 252:199-208
Ependymal cells have an essential role in regulating the dynamics of the cerebrospinal fluid flow by the movement of their multiple cilia. Impaired generation or function of cilia could cause hydrocephalus due to the disordered dynamics of the cerebr